Placenta and its status in varicosity disease in multiparas

The clinical course of pregnancy and he morphological features of the placenta were studied in 32 multiparas with varicosity disease and in 15 healthy multiparas. The chorionic villi were found to have signs of local disseminated intravascular coagulation (microthrombosis and hemorrhages), the intervillous space showed foci of necrotizing villi, their infarction, fibrinoid deposits in the basement membrane area, and fibrinoid agglutination of villi; the villous stroma and intervillous space exhibited foci of calcification. The placental morphological findings suggest chronic compensated insufficiency; moderate involutive-dystrophic and compensatory-adaptive processes were detectable in placental tissue.

pregnancy, multiparas, varicosity disease, placenta