ROLE OF BIOCHEMICAL MARKERS AND CERVICOMETRY IN THE DIAGNOSIS OF THREATENED PRETERM BIRTH


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Resumo

Objective. To assess the PartoSure test and cervicometry used to define the risk of preterm birth. Subjects and methods. A test for PAMG-1 and cervicometry were performed in 49 patients with threatened preterm birth. Time to delivery (TTD) intervals was estimated if labor occurred. Results. The test was positive (+) in 100% of cases if the cervical canal length (L) was 4 1.5 cm (6% of the patients); at the same time, preterm births occurred in 75% (TTD=18 and 44 hours). When L was 1.5 to 3 cm, the positive (+) test was seen in only 1 case (85%) (TTD=140 hours). The relationship between the results of the test and cervicometry, their diagnostic sensitivity, specificity, the prognostic value of positive and negative results were determined. Conclusion. The PartoSure test in conjunction with cervicometry is a technique to determine whether threatened preterm birth may be managed in an outpatient setting.

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Sobre autores

Vyacheslav Bolotskikh

D.O. Ott Research Institute of Obstetrics and Gynecology, North-Western Branch, Russian Academy of Medical Sciences

Email: docgin@yandex.ru
Doctor of Medicine, M.D., Head of the 2nd prenatal unit Saint Petersburg 199034, Mendeleyevskaya line 3, Russia

Vera Borisova

D.O. Ott Research Institute of Obstetrics and Gynecology, North-Western Branch, Russian Academy of Medical Sciences

Email: borisova.ver@gmail.com
Candidate of Medicine, research assistant Saint Petersburg 199034, Mendeleyevskaya line 3, Russia

Bibliografia

  1. Айламазян Э.К., Кулаков В.И., Радзинский В.Е., Савельева Г.М., ред. Акушерство. Национальное руководство. М.: ГЭОТАР-Медиа; 2007. 1200 с.
  2. Gabbe S.G., Niebyl J.R., Simpson J.L., Landon M.B., Galan H.L., Jauniaux E.R.M., Driscoll D.A., eds. Obstetrics: normal and problem pregnancies. 6th ed. Saunders Elsevier; 2012. 1312 p.
  3. Rahkonen L., Unkila-Kallio L., Nuutila M., Sainio S., Saisto T., Rutanen E.M., Paavonen J. Cervical length measurement and cervical phosphorylated insulin-like growth factor binding protein-1 testing in prediction of preterm birth in patients reporting uterine contractions. Acta Obstet. Gynecol. Scand. 2009; 88(8): 901 ? 8.
  4. Kiefer D.G., Vintzileos A.M. The utility of fetal fibronectin in the prediction and prevention of spontaneous preterm birth. Rev. Obstet. Gynecol. 2008 Summer; 1(3):106 ? 12.
  5. Bittar R.E., da Fonseca E.B., de Carvalho M.H., Martinelli S., Zugaib M. Predicting preterm delivery in asymptomatic patients with prior preterm delivery by measurement of cervical length and phosphorylated insulinlike growth factor-binding protein-1. Ultrasound Obstet. Gynecol. 2007; 29(5): 562 ? 7.
  6. Sukchaya K., Phupong V. A comparative study of positive rate of placental a-microglobulin-1 test in preterm pregnant women with and without uterine contraction. J. Obstet. Gynaecol. 2013; 33(6): 566 ? 8.
  7. Lee S.M., Romero R., Park J.W., Kim S.M., Park C.W., Korzeniewski S.J. et al. The clinical significance of a positive Amnisure test(™) in women with preterm labor and intact membranes. J. Matern. Fetal Neonatal Med. 2012; 25(9): 1690 ? 8.
  8. Nikolova T., Bayev O., Nikolova N., Di Renzo G.C. Evaluation of a novel placental alpha microglobulin-1 (PAMG-1) test to predict spontaneous preterm delivery. J. Perinat. Med. 2014; 42(4): 473 ? 7.
  9. Paternoster D., Riboni F., Vitulo A., Plebani M., DellAvanzo M., Battagliarin G. et al. Phosphorylated insulin-like growth factor binding protein-1 in cervical secretions and sonographic cervical length in the prediction of spontaneous preterm delivery. Ultrasound Obstet. Gynecol. 2009; 34(4): 437? 40.

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