ROLE OF BIOCHEMICAL MARKERS AND CERVICOMETRY IN THE DIAGNOSIS OF THREATENED PRETERM BIRTH


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Abstract

Objective. To assess the PartoSure test and cervicometry used to define the risk of preterm birth. Subjects and methods. A test for PAMG-1 and cervicometry were performed in 49 patients with threatened preterm birth. Time to delivery (TTD) intervals was estimated if labor occurred. Results. The test was positive (+) in 100% of cases if the cervical canal length (L) was 4 1.5 cm (6% of the patients); at the same time, preterm births occurred in 75% (TTD=18 and 44 hours). When L was 1.5 to 3 cm, the positive (+) test was seen in only 1 case (85%) (TTD=140 hours). The relationship between the results of the test and cervicometry, their diagnostic sensitivity, specificity, the prognostic value of positive and negative results were determined. Conclusion. The PartoSure test in conjunction with cervicometry is a technique to determine whether threatened preterm birth may be managed in an outpatient setting.

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About the authors

Vyacheslav Mixajlovich Bolotskikh

D.O. Ott Research Institute of Obstetrics and Gynecology, North-Western Branch, Russian Academy of Medical Sciences

Email: docgin@yandex.ru
Doctor of Medicine, M.D., Head of the 2nd prenatal unit Saint Petersburg 199034, Mendeleyevskaya line 3, Russia

Vera Yur’evna Borisova

D.O. Ott Research Institute of Obstetrics and Gynecology, North-Western Branch, Russian Academy of Medical Sciences

Email: borisova.ver@gmail.com
Candidate of Medicine, research assistant Saint Petersburg 199034, Mendeleyevskaya line 3, Russia

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