The clinical and economic efficiency of direct electrocardiography with ST-segment analysis in the evaluation of fetal status


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Resumo

Objective. To compare the clinical and economic efficiency of traditional cardiotocography (CTG) and its combined use with direct fetal electrocardiography (ECG) and automatic analysis of ST-segment changes for the early detection of intranatal fetal hypoxia. Subjects and methods. A prospective study of the course of pregnancy and delivery was conducted in 480 women at the V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology. The authors designed a decisionmaking model (TreeAge Pro Inc), by which a cost-effectiveness analysis was used to compare 2 strategies: CTG and ECG in combination with direct ECG (with automatic ST-segment analysis) to determine the minimum cost of the birth of a baby without asphyxia. Results. With the use of traditional fetal CTG at birth, the chance of giving birth to a baby without severe asphyxia was 91% versus 97% with that of a combination of CTG and ECG (that was 70 and 82% during cesarean section and 96 and 98% during vaginal delivery, respectively). The mean cost of birth per healthy baby (without severe asphyxia and consideration of expenses on neonatal management and rehabilitation) was 54,645.78 and 42,903/72 rubles with the use of CTG and CTG + ECG, respectively. Conclusion. CTG in combination with direct fetal ECG with automatic ST-segment analysis makes it possible to effectively and timely monitor fetal status during an active delivery stage. The use of this procedure can substantially reduce the cost of labor induction.

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Sobre autores

O. Eremina

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: olga.erem@gmail.com
specialist of department of ultrasound diagnostic

Nataliya Dolgushina

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: n_dolgushina@oparina4.ru
M.D., Ph.D., M.P.H., Head of R&D Department

O. Baev

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: metod_obsgyn@hotmail.com
MD, PhD, professor, the head of Maternity Department

Bibliografia

  1. Барашнев Ю.И. Клинико-морфологическая характеристика церебральных расстройств при гипоксически-ишемических энцефалопатиях. Акушерство и гинекология. 2000; 5: 39-42. [Barashnev Yu.I. Clinical and morphological characteristics of cerebral disorders with hypoxic-ischemic encephalopathy. Akusherstvo i ginekologiya/Obstetrics and gynecology. 2000; 5: 39-42. (in Russian)]
  2. Салдусова О.А. Интранатальная гипоксия плода при фетоплацентарной недостаточности: автореф. дисс.. канд. мед. наук. М.; 2006. 17с. [Saldusova O.A. Intrapartum fetal hypoxia with placental insufficiency. Abstract. diss. Moscow; 2006. 17p. (in Russian)]
  3. Leigh S., Granby P., Turner M., Wieteska S., Haycox A., Collins B. The incidence and implications of cerebral palsy following potentially avoidable obstetric complications: a preliminary burden of disease study. BJOG. 2014; 121(13): 1720-8.
  4. Reinhard J., Hayes-Gill B.R. Comparison of non-invasive fetal electrocardiogram to Doppler cardiotocogram during the 1st stage of labor. J. Perinat. Med. 2010; 38(2): 179-85.
  5. Alfirevic Z., Devane D., Gyte G.M. Continuous cardiotocography (CTG) as a form of electronic fetal monitoring (EFM) for fetal assessment during labour. Cochrane Database Syst. Rev. 2013; (5): CD006066.
  6. Vijgen S.M., Westerhuis M.E., Opmeer B.C., Visser G.H., Moons K.G., Porath M.M. et al. Cost-effectiveness of cardiotocography plus ST analysis of the fetal electrocardiogram compared with cardiotocography only. Acta Obstet. Gynecol. Scand. 2011; 90(7): 772-8.
  7. Heintz E., Brodtkorb T.H., Nelson N., Levin L.A. The long-term cost-effectiveness of fetal monitoring during labour: a comparison of cardiotocography complemented with ST analysis versus cardiotocography alone. BJOG. 2008; 115(13): 1676-87.

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