PSYCHOLOGICAL ASPECTS OF TERMINATION OF EARLY-STAGE NON-DEVELOPING PREGNANCY: A RANDOMIZED CLINICAL TRIAL

In the last decades various methods to terminate pregnancy have been widely introduced in the Kyrgyz Republic, but little attention has been paid to their impact on the psychological status of a woman. Objective. To determine the rate of depressive disorders and to compare psychological outcomes in women before and after termination of early-stage non-developing pregnancy. Subjects and methods. This was a non-blinded randomized cohort trial. A sample consisted of633 women at less than 12 weeks+6days of gestation; of these, 399 women had non-developedpregnancy. Testing was carried out using the Tsungpre-diagnosis depression scale. Results. The pre-abortion rate of psychological disorders was 30.3%. There were 72.9% of mild depression cases in the structure of depressive disorders. The post-abortion rate of depression was increased by 6.0%. Following medical abortion with mefipristone in combination with misoprostol, the rate of mild depressive disorders (36.4%) was, with high statistical significance, greater than that with misoprostol alone (22.3 %) (φетr 2.598; P < 0.01) and surgical abortion (20.2%) (φemr 2.872; P < 0.001). Conclusion. The high level of depressive disorders in women with early pregnancy suggests that there is a need to elaborate programs for the early detection of psychological disorders and the choice of an abortion method.

missed abortion, early-stage non-developing pregnancy, missed abortion, psychological disorders, medical and surgical abortion