Early predictors of preeclampsia
- Autores: Dubrovina S.O.1, Mutsalkhanova U.S.1, Vasilyeva V.V.1
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Afiliações:
- Rostov State Medical University
- Edição: Nº 10 (2018)
- Páginas: 47-51
- Seção: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/248262
- DOI: https://doi.org/10.18565/aig.2018.10.47-51
- ID: 248262
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Resumo
Objective. To investigate the clinical, anamnestic, and biochemical predictors of preeclampsia. Subjects and methods. Clinical, anamnestic, and biochemical examinations were performed in pregnant women, who later formed two groups: pregnant women with late-onset moderate preeclampsia and patients without preeclampsia. Results. The significant clinical markers for late-onset preeclampsia were shown to be increases in body mass index and mean blood pressure at 11-13 weeks’ gestation. The pregnant women with preeclampsia were found to have significantly higher serum levels of retinol-binding protein 4 and disintegrin and metalloproteinase 12. The anamnestic predictors of preeclampsia were ascertained to be hypertension in the history, chronic pyelonephritis, and preeclampsia in previous pregnancies. Conclusion. A prognostic model based on the co-use of the studied predictors has been developed for the early prediction of late-onset moderate preeclampsia.
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Sobre autores
Svetlana Dubrovina
Rostov State Medical University
Email: s.dubrovina@gmail.com
MD, PhD, Professor, the main scientific researcher
Ulduz Mutsalkhanova
Rostov State Medical University
Email: yulduzka111@mail.ru
postgraduate student
Valentina Vasilyeva
Rostov State Medical University
Email: v.vasiljeva1965@mail.ru
PhD, assoc. prof., leading researcher
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