Prevalence of hpv-infection and regional peculiarities of the risk factors of associated cervical diseases among the indigenous people of North Russia

Purpose. To assess the prevalence and age range of HPV infections of high oncogenic types and regional characteristics of risk factors of associated cervical diseases among women of small indigenous peoples of the North (Khanty-Mansi Autonomous Okrug - Yugra). Material and methods. A one-time selective population-based cross-sectional study of299 women was conducted. Used questionnaires, research on HPV (material obtained through self-collection using Qvintip kits), STIs, microscopy and cytological examination of cervical smears. Results. The prevalence of HPV infection with high oncogenic risk was 13% (38/299), with prevalence of types 16, 31 and 51, mainly in women aged 30 to 50 years (60.5%, 23/38). Of these, atypical intraepithelial lesions of the cervix were detected in 23.6%, including HSIL - in 10.5%. Regional features of risk factors include the presence of bacterial vaginosis in history and currently, diseases of the lower part of the genital tract of inflammatory nature, as well as high parity, a large number of sexual partners, the presence of gynecological diseases and operations on the genitals in history. Conclusions. Among women of small indigenous peoples of the North (Khanty-Mansi Autonomous Okrug-Ugra), HPV infection does not exceed world indicators, but has regional characteristics of risk factors. Independent sampling of material for laboratory research on HPV using the Qvintip kit is promising for reaching the necessary number of people by organized screening.

human papillomavirus, cervical cancer, atypical intraepithelial lesions of the cervix, risk factors, screening, Qvintip kit