Treatment for female external genital lichen sclerosus: from standards to innovations
- Autores: Sokolova A.V.1, Apolikhina I.A.1
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Afiliações:
- National Medical Research Center for Obstetrics, Gynecology and Perinatology named after V.I. Kulakov
- Edição: Nº 7 (2020)
- Páginas: 37-46
- Seção: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/248833
- DOI: https://doi.org/10.18565/aig.2020.7.37-46
- ID: 248833
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Resumo
Lichen sclerosus is one of the most common female external genital diseases. The limiting factor for the success of treatment for vulvar lichen sclerosus is a lack of consensus on the etiopathogenesis of the disease and accordingly targeted treatments. Topical glucocorticosteroids and calcineurin inhibitors are now the first-line therapy. Despite a variety of drugs for the treatment of vulvar lichen sclerosus, there are more and more cases of resistance and adverse reactions to traditional therapy, and considering the young age of patients, the search for new technologies in the treatment of vulvar lichen sclerosus is becoming urgent. The article reviews methods for treating the disease in accordance with international protocols and Russian recommendations. In addition, it describes minimally invasive techniques, such as high-frequency focused ultrasound (HIFU), photothermal vulvar tissue reconstruction using carbon dioxide, erbium, and neodymium lasers, platelet-rich plasma (PRP), and autologous stem-cell transplantation, which are currently actively used and have a great therapeutic potential to influence the foci of lichen sclerosus.
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Sobre autores
Anastasia Sokolova
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after V.I. Kulakov
Email: stasia0590@mail.ru
MD, obstetrician&gynecologist, post-graduate student
Inna Apolikhina
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after V.I. Kulakov
Email: apolikhina@inbox.ru
MD, obstetrician&gynecologist, professor
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