Pregestational and gestational diabetes mellitus as risk factors for predicting the development of congenital anomalies in newborns
- Autores: Postoev V.A.1, Telkova A.A.1, Maevskaya P.S.1, Postoeva A.V.1, Usynina A.A.1, Grjibovski A.M.1,2
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Afiliações:
- Northern State Medical University, Ministry of Health of the Russian Federation
- Northern (Arctic) Federal University named after M.V. Lomonosov
- Edição: Nº 11 (2023)
- Páginas: 78-86
- Seção: Original Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/626073
- DOI: https://doi.org/10.18565/aig.2023.125
- ID: 626073
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Resumo
Objective: This study aimed to estimate the influence of maternal pregestational and gestational diabetes mellitus on the risk of congenital anomalies in newborns.
Materials and methods: We conducted a cohort study using data from the Murmansk and Arkhangelsk County birth registries, which contain information on the health of pregnant women and neonatal diaseses in newborns of 134,884 pregnancies.
Results: From 2006 to 2017, 4862 newborns with congenital anomalies were identified, resulting in a prevalence of 36.2 per 1,000 births. Pregnant women with pregestational diabetes mellitus had a higher risk of giving birth to babies with anomalies of the eye, ear, face, and neck, circulatory system, and other congenital anomalies (Q80-Q89), including multiple anomalies. Pregnant women with gestational diabetes mellitus had a higher risk of having children with respiratory system anomalies.
Conclusion: Diabetes mellitus in women increases the risk of congenital anomalies in their children. Prognostic models developed to determine the risk of congenital anomalies should include information regarding the presence of maternal diabetes.
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Sobre autores
Vitaly Postoev
Northern State Medical University, Ministry of Health of the Russian Federation
Autor responsável pela correspondência
Email: ispha@nsmu.ru
ORCID ID: 0000-0003-4982-4169
Cand. Sci. (Med), Ph.D., Acting Head of the Department of Methodology of Scientific Research, Head of the Arkhangelsk International School of Public Health Northern State Medical University
Rússia, 163069, Arkhangelsk, Troitsky Ave., 51Alena Telkova
Northern State Medical University, Ministry of Health of the Russian Federation
Email: ispha@nsmu.ru
ORCID ID: 0009-0002-1472-0546
Rússia, 163069, Arkhangelsk, Troitsky Ave., 51
Polinа Maevskaya
Northern State Medical University, Ministry of Health of the Russian Federation
Email: ispha@nsmu.ru
ORCID ID: 0009-0004-4486-6225
Rússia, 163069, Arkhangelsk, Troitsky Ave., 51
Anna Postoeva
Northern State Medical University, Ministry of Health of the Russian Federation
Email: ispha@nsmu.ru
ORCID ID: 0000-0003-3749-0173
Cand. Sci. (Med),Associate Professor at the Department of Hospital Therapy and Endocrinology
Rússia, 163069, Arkhangelsk, Troitsky Ave., 51Anna Usynina
Northern State Medical University, Ministry of Health of the Russian Federation
Email: perinat@mail.ru
ORCID ID: 0000-0002-5346-3047
Dr. Med. Sci., Ph.D., Head of the Department of Neonatology and Perinatology
Rússia, 163069, Arkhangelsk, Troitsky Ave., 51
Andrej Grjibovski
Northern State Medical University, Ministry of Health of the Russian Federation; Northern (Arctic) Federal University named after M.V. Lomonosov
Email: a.grjibovski@yandex.ru
ORCID ID: 0000-0002-5464-0498
MD, Head of the Division for Research and Innovations, Chief researcher at the Arctic biomonitoring laboratory Northern (Arctic) Federal University
Rússia, 163069, Arkhangelsk, Troitsky Ave., 51; 163001, Arkhangelsk, 17 Severnaya Dvina Emb.Bibliografia
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