EFFICIENCY OF USING EXTRACORPOREAL BLOOD PURIFICATION TECHNIQUES AND MEDICAL OZONE IN PLACENTAL INSUFFICIENCY TREATMENT


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Objective. Optimization of complex placental insufficiency treatment by using of both extracorporeal blood purification techniques and medical ozone. Methods. 127 pregnant women with placental insufficiency were divided into 2 groups depending on used therapeutic methods. Pre-conceptional status, pregnancy course, labor, postpartum period, newborns were assessed. Group 1 (study group) composed 58 pregnant women with placental insufficiency in which extracorporeal blood purification techniques and medical ozone treatment were included in complex therapy. Group 2 (comparison group) composed of 69 women with standard methods of placental insufficiency treatment. Results. The pregnancy complicated by placental insufficiency creates negative impact on adequate production and functioning of growth factors. Using traditional therapeutic methods in patients with placental insufficiency has led to considerable decrease in PGF level and increase in VEGF level during pregnancy compared to study group. It could be explained with higher therapeutic efficiency in the study group. Using extracorporeal blood purification techniques and medical ozone treatment in the study group resulted in significant reduction of complication rates during the labor and postpartum period, so as to more favorable perinatal outcomes. Conclusion. Thus, the current research has shown high-potency of extracorporeal blood purification techniques in complex therapy of placental insufficiency.

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作者简介

O. MIKHAILOVA

V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of the Russian Federation

Email: o_mihaylova@oparina4.ru
Moscow, Russia

T. FEDOROVA

V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of the Russian Federation

Email: t_fyodorova@oparina4.ru
Moscow, Russia

V. TYUTYUNNIK

V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of the Russian Federation

Email: tioutiounnik@mail.ru
Moscow, Russia

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