ROLE OF EARLY SCREENING FOR GESTATIONAL DIABETES MELLITUS IN OPTIMIZING PERINATAL OUTCOMES


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Abstract

Objective. To assess the role of early screening for gestational diabetes mellitus (GDM) in optimizing perinatal outcomes. Subject and methods. A prospective comparatively study was conducted in 2 groups of pregnant women with GDM. The time for detection of GDM was 14.5±7.5 and 27.2±7.6 weeks in Groups 1 (n=44) and 2 (n=97), respectively. In both groups, the diagnosis of GDM was verified using the WHO criteria (1999). There were no differences between the groups in treatment policies for GDM. Results. The early diagnosis of GDM was accompanied 1.8-, 3.1-, and 2-fold less frequently by fetoplacental insufficiency, macrosomia, and cesarean section, respectively. There were no cases of preterm delivery and neonatal hypoglycemia in Group 1 whereas Group 2 showed these conditions in 20.6 and 11.3% of cases, respectively. Analyzing our results according to the new criteria for GDM (Russian National Consensus, 2012) revealed a fasting venous plasma glucose level of ≥5.1 mmol/l in 88.6% of the patients who were found to have GDM according to the WHO criteria and oral glucose tolerance test (OGTT). Conclusion. The early detection of GDM and hence the timely correction of carbohydrate metabolic disturbances permit the optimization of perinatal outcomes. The GDM diagnostic criteria recommended by the Russian National Consensus allow an early screening in all pregnant women without being divided into risk groups and a first-trimester diagnosis of the disease without carrying out an OGTT in most patients.

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About the authors

E. G DERYABINA

Ural Research Institute of Maternity and Infancy Care, Ministry of Health of the Russian Federation

Email: helen_mic@mail.ru
Yekaterinburg

N. V BASHMAKOVA

Ural Research Institute of Maternity and Infancy Care, Ministry of Health of the Russian Federation

Email: zamdirnir@k66.ru
Yekaterinburg

D. M LARKIN

Ural Research Institute of Maternity and Infancy Care, Ministry of Health of the Russian Federation

Email: larkin-78@mail.ru
Yekaterinburg

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