INDOLE CARBINOL IS A MULTITARGETED THERAPY OPTION FOR CYCLIC MASTODYNIA
- 作者: KISELEV V.I1, SMETNIK V.P2, SUTURINA L.V3, SELIVANOV S.P4, RUDAKOVA E.B5, RAKHMATULLINA I.R6, ANDREYEVA E.N7, FADEYEVA N.I8, KHASANOV R.S.9, KULAGINA N.V10, ROZHKOVA N.I11, ARTYMUK N.V12, GAVISOVA A.A2, MUIZHNEK E.L13, KUZNETSOV I.N14, DRUKH V.M15
-
隶属关系:
- National Research Center "Kurchatov Institute"
- Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia Federation
- Research Centre for Family Health and Human Reproduction Problems, Siberian Branch, Russian Academy of Medical Sciences
- Therapeutic and Diagnostic Center, Tomsk 5Omsk State Medical Academy, Ministry of Health of Russia Federation
- Omsk State Medical Academy, Ministry of Health of Russia Federation
- Republican Clinical Oncology Dispensary, Ministry of Health of the Republic of Bashkortostan, Ufa 7Endocrinology Research Center, Ministry of Health of the Russian Federation
- Endocrinology Research Center, Ministry of Health of the Russian Federation
- Altai State Medical University, Ministry of Health of Russia Federation
- Republican Clinical Oncology Dispensary, Ministry of Health of Russia of Tatarstan
- I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia Federation
- Russian X-ray Radiology Research Center, Ministry of Health of Russia Federation
- Kemerovo State Medical Academy, Ministry of Health of Russia Federation
- ZAO "MiraxBioPharma"
- A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia Federation
- ZAO «IlmixGroup»
- 期: 编号 7 (2013)
- 页面: 56-62
- 栏目: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/247021
- ID: 247021
如何引用文章
详细
全文:
作者简介
V. KISELEV
National Research Center "Kurchatov Institute"
Email: vkis10@mail.ru
V. SMETNIK
Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia Federation
Email: verasmetnik@mail.ru
L. SUTURINA
Research Centre for Family Health and Human Reproduction Problems, Siberian Branch, Russian Academy of Medical Sciences
Email: lsuturina@mail.ru
Irkutsk
S. SELIVANOV
Therapeutic and Diagnostic Center, Tomsk 5Omsk State Medical Academy, Ministry of Health of Russia Federation
Email: am@am.tom.ru
Omsk
E. RUDAKOVA
Omsk State Medical Academy, Ministry of Health of Russia Federation
Email: doctor_rudakova@mail.ru
Omsk
I. RAKHMATULLINA
Republican Clinical Oncology Dispensary, Ministry of Health of the Republic of Bashkortostan, Ufa 7Endocrinology Research Center, Ministry of Health of the Russian Federation
Email: rahmatullina@rambler.ru
E. ANDREYEVA
Endocrinology Research Center, Ministry of Health of the Russian Federation
Email: endogin@mail.ru
N. FADEYEVA
Altai State Medical University, Ministry of Health of Russia Federation
Email: nat2fad@hotmail.com
Barnaul
R. KHASANOV
Republican Clinical Oncology Dispensary, Ministry of Health of Russia of Tatarstan
Email: rkod.mzrt@tatar.ru
Kazan
N. KULAGINA
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia Federation
Email: dr.Kulagina@mail.ru
Saint Petersburg
N. ROZHKOVA
Russian X-ray Radiology Research Center, Ministry of Health of Russia Federation
Email: rozhkova@rncrr.ru
N. ARTYMUK
Kemerovo State Medical Academy, Ministry of Health of Russia Federation
Email: artymuk@kemtel.ru
A. GAVISOVA
Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia Federation
Email: gavialla@yandex.ru
E. MUIZHNEK
ZAO "MiraxBioPharma"
Email: MuyzhnekEL@ilmixgroup.ru
I. KUZNETSOV
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia Federation
Email: kuznetsovin@ilmixgroup.ru
V. DRUKH
ZAO «IlmixGroup»
Email: DruhVM@ilmixgroup.ru
参考
- Bradlow H.L., Michnovicz J.J., Halper M., Miller D.G., Wong G.Y., Osborne M.P. Long-term responses of women to indole-3-carbinol or a high fiber diet. Cancer Epidemiol. Biomarkers Prev., 1994; 3(7): 591-5.
- Morimoto Y., Conroy S.M., Pagano I.S., Isaki M., Franke A.A., Nordt F.J., Maskarinec G. Urinary estrogen metabolites during a randomized soy trial. Nutr. Cancer. 2012; 64(2): 307-14.
- Киселев В.И., Ляшенко А.А. Молекулярные механизмы регуляции гиперпластических процессов. М.: Димитрейд График Групп; 2005. 346 с.
- Рожкова Н.И., Меских Е.В. Лечение доброкачественных заболеваний молочной железы. Опухоли репродуктивной системы. 2007; 4: 23-4.
- Серов В.Н., Прилепская В.Н., Овсянникова Т.В. Гинекологическая эндокринология. М.: МЕДпресс-информ; 2008. 532 с.
- Идрисова Э.А., Бадгоева О.Х., Власов Р.С., Макарова И.И., Гуриев Т.Д. Сочетание гиперпролиферативных заболеваний матки и молочных желез: возможности таргентной терапии. Проблемы репродукции: Материалы IV международного конгресса по репродуктивной медицине. 2010; Спец. выпуск: 186-7.
- Jellinck P.H., Forkert P.G., Riddick D.S., Okey A.B., Michnovicz J.J., Bradlow H.L. Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation. Biochem. Pharmacol. 1993; 43: 1129-36.
- Szaefer H., Licznerska B., Krajka-Kuźniak V., Bartoszek A., Baer-Dubowska W. Modulation of CYP1A1, CYP1A2 and CYP1B1 expression by cabbage juices and indoles in human breast cell lines. Nutr. Cancer. 2012; 64(6): 879-88.
- Ашрафян Л.А. Опухоли репродуктивных органов (этиология и патогенез). М.: Димитрейд График Групп; 2007. 216 с.
- Weng J.R., Omar H.A., Kulp S.K., Chen C.S. Pharmacological exploitation of indole-3-carbinol to develop potent antitumor agents. Mini Rev. Med. Chem. 2010; 10(5): 398-404.
- Sarkar F.H., Li Y. Harnessing the fruits of nature for the development of multi-targeted cancer therapeutics. Cancer Treat. Rev. 2009; 35(7): 597-607.
- Ahmad A., Sakr W.A., Rahman K.M. Anticancer properties of indole compounds: mechanism of apoptosis induction and role in chemotherapy. Curr. Drug Targets. 2010; 11(6): 652-66.
- Hong C., Firestone G.L., Bjeldanes L.F. Bcl-2 family-mediated apoptotic effects of 3,3’-diindolylmethane (DIM) in human breast cancer cells. Biochem. Pharmacol. 2002; 63(6): 1085-97.
- Nachshon-Kedmi M., Yannai S., Fares F.A. Induction of apoptosis in human prostate cancer cell line, PC3, by 3,3’-diindolylmethane through the mitochondrial pathway. Br. J. Cancer. 2004; 91(7): 1358-63.
- Matsuzaki Y., Koyama M., Hitomi T., Kawanaka M., Sakai T. Indole-3-carbinol activates the cyclin-dependent kinase inhibitor p15(INK4b) gene. FEBS Lett. 2004; 576(1-2): 137-40.
- Acharya A., Das I., Singh S., Saha T. Chemopreventive properties of indole-3-carbinol, diindolylmethane and other constituents of cardamom against carcinogenesis. Recent Pat. Food Nutr. Agric. 2010; 2(2): 166-77.
- Saw C.L., Cintrón M., Wu T.Y., Guo Y., Huang Y., Jeong W.S., Kong A.N. Pharmacodynamics of dietary phytochemical indoles I3C and DIM: Induction of Nrf2-mediated phase II drug metabolizing and antioxidant genes and synergism with isothiocyanates. Biopharm. Drug Dispos. 2011; 32(5): 289-300.
- Kunimasa K., Kobayashi T., Kaji K., Ohta T. Antiangiogenic effects of indole-3-carbinol and 3,3’-diindolylmethane are associated with their differential regulation of ERK1/2 and Akt in tube-forming HUVEC. J. Nutr. 2010; 140(1): 1-6.
- Wong G.Y., Bradlow L., Sepkovic D., Mehl S., Mailman J., Osborne M.P. Dose-ranging study of indole-3-carbinol for breast cancer prevention. J. Cell Biochem. 1997; 28-29(Suppl.): 111-6.
- Terry P., Wolk A., Persson I., Magnusson C. Brassica vegetables and breast cancer risk. JAMA. 2001; 285(23): 2975-7.
- Meng Q., Yuan F., Goldberg I.D., Rosen E.M., Auborn K., Fan S. Indole-3-carbinol is a negative regulator of estrogen receptor-alpha signaling in human tumor cells. J. Nutr. 2000; 130(12): 2927-31.
- Reed G.A., Peterson K.S., Smith H.J., Gray J.C., Sullivan D.K., Mayo M.S. et al. A phase I study of indole-3-carbinol in women: tolerability and effects. Cancer Epidemiol. Biomarkers Prev. 2005; 14(8): 1953-60.
- Reed G.A., Arneson D.W., Putnam W.C., Smith H.J., Gray J.C., Sullivan D.K. et al. Single-dose and multiple-dose administration of indole-3-carbinol to women: pharmacokinetics based on 3,3’-diindolylmethane. Cancer Epidemiol. Biomarkers Prev. 2006; 15(12): 2477-81.