USE OF LACTULOSE IN THE TREATMENT OF CONSTIPATION DURING PREGNANCY AND POSTPARTUM
- 作者: SOKUR T.N1, DUBROVINA N.N1
-
隶属关系:
- Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
- 期: 编号 8 (2013)
- 页面: 103-107
- 栏目: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/247074
- ID: 247074
如何引用文章
开放存取
##reader.subscriptionAccessGranted##
详细
Subject and methods. 150 women suffering from constipation during pregnancy and postpartum were examined. Results. The investigation revealed that the performed course of therapy resulted in stool normalization and a sense of full bowel emptying in 96.7% of the pregnant women; only 3.3% of the examinees did not benefit from performed therapy. It is also important to note that Lactulose did not induce violent intestinal motility that provoked the symptoms of threatened abortion and premature birth. Conclusion. Lactulose is the drug of choice to treat constipation during pregnancy and postpartum due to its high efficacy, good tolerance, and no negative maternal and fetal effect. Furthermore, it has a prebiotic effect, restores enteric microflora, controls Candida infection, and sanitizes the maternal passages.
全文:
作者简介
T. SOKUR
Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
Email: socur@bk.ru
Moscow, Russia
N. DUBROVINA
Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
Email: dubrovinan@mail.ru
Moscow, Russia
参考
- Anderson A.S. Constipation durin pregnance: incidence and methods used in its treatment in groupe of Cambridgeshire women. Health Visit. 1984; 57: 363—4.
- Smouth A.J.M.P., Akkermans L.M.A. Normal and disturbed motility of the gastroentestinal trakt. Petersfield; 1992. 312p.
- Бурков С.Г. Заболевания органов пищеварения у беременных. М.: КРОН-ПРЕСС; 1996. 224с.
- Назарова Е.К., Гиммельфарб Е.И., Созаева Л.Г. Микроциноз влагалища и его нарушения (этиология, патогенез, клиника, лабораторная диагностика). Клиническая лабораторная диагностика. 2003; 2: 25—32.
- Подзолкова Н.М., Халиф И.Л., Назарова С.В., Гвасалия А.Г. Биоценоз толстой кишки и цервикального канала беременных на фоне лечения хронического запора. Проблемы беременности. 2004; 8: 51—7.
- Халиф И.Л., Подзолкова Н.М.,Конович Е.А., Назарова С.В., Гвасалия А.Г. Влияние запора у беременных на состояние кишечной и генитальной микрофлоры и проницаемость кишечника. Российские медицинские вести. 2004; 9(1): 43—7.
- Серов В.Н., Жаров Е.В., Добровольская И.В. Устранение запоров у беременных и родильниц. Журнал Российского общества акушеров-гинекологов. 2009; 3: 8—11.
- Dukas L., Willett W., Giovannucci E. Association between physical activity, fiber intake, and other lifestyle variables and constipation in a study of women. Am. J. Gastroenterol. 2003; 98(8): 1790—6.
- Sykes N.P. Current approaches to the management of constipation. Cancer Surv. 1994; 21: 137—46.
- Talley N. Definitions, epidemiology, and impact of chronic constipation. Rev. Gastroenterol. Disord. 2004; 4(Suppl. 2): S3—10.
- Lembo A., Camilleri M. Chronic constipation. N. Engl. J. Med. 2003; 349: 1360—8.
- Шехтман М.М., Положенкова Л.А. Дискинезия толстой кишки у беременных. Гинекология. 2004; 6(5): 49—54.
- Мельник Т.Н., Липовенко Л.Н. Лечение запоров у беременных. Вопросы гинекологии, акушерства и перинатологии. 2003; 2: 103—4.
- Thukral C., Wolf J.L. Therapy insight: drugs for gastrointestinal disorders in pregnant women. Nat. Clin. Pract. Gastroenterol. Hepatol. 2006; 3(5): 256—66.
- Циммерман Я.С. Хронический запор. Диарея. Пермь: ПГМА; 1999. 120с.
补充文件
