Complete zona pellucida removal from blastocysts prior to transfer in a cryo-cycle does not affect the efficiency of in vitro fertilization programs


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Objective. To evaluate the efficiency of in vitro fertilization (IVF) programs during the transfer of blastocysts in a cryo-cycle with their zona pellucida (ZP) removal. Material and methods. An experimental group included 209 patients whose embryos before transfer were subjected to complete mechanical ZP removal; a control group consisted of222patients, in whom blastocysts with intact ZP were used for transfer. The rates of embryo implantation and clinical and progressive clinical pregnancy were estimated. Results. All clinical outcomes of the programs had no statistically significant differences in the group of embryos with the removed ZP and with the embryos in the control group, including subgroups of patients younger and older than 36 years of age. Conclusion. Complete zona pellucida removal from blastocysts prior to their transfer in a cryo-cycle does not affect the efficiency of IVFprograms.

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作者简介

Konstantin Kirienko

AltraVita Clinic of Human Reproduction, OOO "ECO CENTER"

Email: kkiriyenko@rambler.ru

Valentina Apryshko

AltraVita Clinic of Human Reproduction, OOO "ECO CENTER"; M.V. Lomonosov Moscow State University

Email: supermycolog@mail.ru

Anna Mironova

AltraVita Clinic of Human Reproduction, OOO "ECO CENTER"; N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences

Margarita Kharitonova

AltraVita Clinic of Human Reproduction, OOO "ECO CENTER"

Email: ritasarc@mail.ru

Irina Ermilova

AltraVita Clinic of Human Reproduction, OOO "ECO CENTER"

Email: i_ermilova@altravita.ru

Anna Naumova

AltraVita Clinic of Human Reproduction, OOO "ECO CENTER"

Email: naumo.ann@yandex.ru

Alexey Klepukov

AltraVita Clinic of Human Reproduction, OOO "ECO CENTER"

Email: klepukov@altravita.ru

Anton Bolt

AltraVita Clinic of Human Reproduction, OOO "ECO CENTER"

Email: a_bolt@altravita.ru

Iana Bozina

AltraVita Clinic of Human Reproduction, OOO "ECO CENTER"

Email: yana.bozina@gmail.com

Elena Lebedeva

AltraVita Clinic of Human Reproduction, OOO "ECO CENTER"

Email: lebedester@gmail.com

Ekaterina Simonenko

M.V. Lomonosov Moscow State University

Email: ksimonenko@inbox.ru

Sergey Yakovenko

AltraVita Clinic of Human Reproduction, OOO "ECO CENTER"; M.V. Lomonosov Moscow State University

Email: altravita@mail.ru

参考

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