Modern pharmacotherapy for chronic recurrent cystitis: problems and opportunities


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The paper provides an overview of current global approaches to pharmacotherapy for chronic recurrent cystitis, including non-antibacterial treatments. The urgency of this problem is associated with the extremely high prevalence of the disease in Russia and worldwide. The antimicrobial resistance in uropathogens has increased dramatically over the past two decades. In cases of recurrent cystitis, the routine management tactics for patients is to increase the time of, doses or to expand antibiotic therapy regimens, despite the lack of evidence supporting this treatment strategy. The lowest resistance of E. coli, the main pathogen of urinary tract infections, is noted for fosfomycin (0-2.9%), nitrofurans (0-4.4%) and mecillinam (0-4%).

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作者简介

E. Shikh

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: chih@mail.ru
MD, professor, Department of clinical pharmacology and propaedeutics of internal diseases of the medical faculty

N. Lazareva

I.M. Sechenov First Moscow State Medical University (Sechenov University)

MD, professor , Department of clinical pharmacology and propaedeutics of internal diseases of the medical faculty

E. Rebrova

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: katrina1987@rambler.ru
h.D, associate Professor of the Department of clinical pharmacology and propaedeutics of internal diseases of the medical faculty

A. Ryazanova

olgograd State Medical University

Department of clinical pharmacology and intensive care with a course of clinical pharmacology of fuv, clinical Allergology

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