COMPARISON OF ACTIVE AND EXPECTANT MANAGEMENT OF PREGNANT WOMEN WITH NON-IMMUNE FETAL HYDROPS


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Aim. To compare perinatal outcomes of women with non-immune hydrops fetalis undergoing active and expectant management. Materials and methods. The study comprised all pregnant women with non-immune fetal hydrops, who were managed at the V.I. Kulakov NMRC for OG&P from 2015 to 2020 (n=45). Group 1 (n=30) included pregnant women with non-immune fetal hydrops, who were examined antenatally according to the developed protocol, and some of them received intrauterine treatment (prospective group from 2018 to 2020). Group 2 included 15 pregnant women who received no antenatal examination and treatment (retrospective group from 2015 to 2018). Results. In group 1, the causes of non-immune hydrops fetalis were identified antenatally in 83.3% (25/30) of patients, and in more than a half of them (56.7%), pregnancy management was based on these findings. In group 2, causes of non-immune hydrops fetalis were identified antenatally in 60% (9/15) of patients, and they received no intrauterine treatment. Patients with an active management approach had higher rates of antenatal resolution of non-immune hydrops and higher perinatal survival rates; their newborns had higher Apgar scores and a lower need for resuscitation, mechanical ventilation, and cardiotonic agents. Conclusion. Antenatal identification of non-immune fetal hydrops causes helps guide active pregnancy management, leading to improved perinatal outcomes.

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作者简介

Faina Kadyrberdieva

V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Email: f_kadyrberdieva@oparina4.ru
Ph.D. Student 117997, Russia, Moscow, Ac. Oparina str., 4

Roman Shmakov

V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Email: r_shmakov@oparina4.ru
Dr. Med. Sci., Professor of the RAS, Director of the Institute of Obstetrics 117997, Russia, Moscow, Ac. Oparina str., 4

Ekaterina Bockeria

V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Email: e_bokeriya@oparina4.ru
Dr. Med. Sci., Professor, Head of the 2nd Department of Pathology of Newborns and Premature Babies; Professor at the Department of Neonatology 117997, Russia, Moscow, Ac. Oparina str., 4

Kirill Kostyukov

V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Email: k_kostyukov@oparina4.ru
Ph.D., Diagnostic Medical Sonographer at the Functional and Ultrasound Diagnostics 117997, Russia, Moscow, Ac. Oparina str., 4

Nana Tetruashvili

V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Email: n_tetruashvili@oparina4.ru
Dr. Med. Sci., Head of the 2nd Obstetrics Department of Pathology of Pregnancy 117997, Russia, Moscow, Ac. Oparina str., 4

参考

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