Lymphoepithelioma-like carcinoma of the cervix

Background: Lymphoepithelioma-like carcinoma of the cervix is one of the subtypes of squamous cell carcinoma of the cervix (CC). Taking into consideration the lack of information about this malignant lesion, publishing the experience of diagnosing and treating a rare variant of CC based on morphologically confirmed echographic data is of interest for practical gynecological oncology. Case report: A 41-year-old patient having acyclic profuse bloody vaginal discharge for 3 months underwent transvaginal echography revealing that the subepithelial tissue of the cervix showed a hypoechoic, homogeneous nodular structure with clear, even contours, 10*11*14 mm with intense low-velocity blood flow in the center and around the periphery. Extended colposcopy indicated no abnormal changes. MRI confirmed the presence of an endophytic tumor in the cervix without invasion into the vagina, parametria, bladder, rectum, and regional lymph nodes. Radiowave excision of the cervix removed a tumor growing into the endometrium, which was identified as a lymphoepithelial-like carcinoma. Taking into account the malignant nature of the tumor, the investigators performed laparoscopic nerve-sparing radical extirpation of the uterus with fallopian tubes, parametria, and the upper third of the vagina, as well as pelvic lymphadenectomy, and ovarian transposition. The postoperative follow-up is 9 months. The patient’s condition is satisfactory. Conclusion: In the absence of CC manifestations in the exocervix, transvaginal echography is deemed as a diagnostic tool to detect potentially malignant lesions, rare forms of CC in particular.

cervical cancer, lymphoepithelioma-like carcinoma of the cervix, diagnosis, treatment