Reaction of substituted chalcone with guanidine in the presence of hydrogen peroxide

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Abstract

This work reports the synthesis of a new compound 3 as a result of the reaction (2E)-1-(4-bromophenyl)-3-[5-bromo-2-(prop-2-en-1-yloxy)phenyl]prop-2-en-1-one with guanidine in the presence of hydrogen peroxide. The structure of the resulting product was confirmed by NMR spectroscopy and X-ray diffraction. A probable reaction mechanism is presented.

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About the authors

I. G. Mamedov

Baku State University

Author for correspondence.
Email: bsu.nmrlab@gmail.com
ORCID iD: 0000-0002-5757-9899

Химический факультет

Azerbaijan, ul. Z. Khalilov, 23, Baku, Az-1148

V. N. Khrustalev

Peoples’ Friendship University of Russia (RUDN University); N.D. Zelinsky Institute of Organic Chemistry RAS

Email: bsu.nmrlab@gmail.com
ORCID iD: 0000-0001-8806-2975
Russian Federation, ul. Miklukho-Maklaya, 6, Moscow, 117198 ; Leninsky prosp., 47, Moscow, 119991

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Supplementary files

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2. Fig. 1. The structure of the molecule of compounds 1 and 2 according to X-ray diffraction data

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3. Fig. 2. The structure of the molecule of compound 3 according to X-ray diffraction data

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4. Scheme

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5. Content

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