Vol 21, No 2 (2015)

The data of electronic questionnaire “The passport of oncological dispensary” was used for monitoring of effectiveness of oncological care support of population in 20 regions of the Russian Federation implementing public programs of health care development in 2009 and 2010. The evaluation was given concerning development of material technical base and manpower of oncological service, effectiveness of preventive activities in the regions with total population more than 31 millions individuals. The development and implementation of preventive programs of federal and regional level, activation of activity and numbers of examination and primary oncological rooms based in curative preventive institutions permits to increase identification of patients with early stages of disease that significantly impacts effectiveness of specific treatment and benevolent outcome.

The article deals with comparative analysis of average duration of treatment victims with different forms of acute intoxications of chemical etiology in 2006 and 2013 in Omsk. It is established that in 2013 duration of hospitalization increased under light forms of acute drug intoxications, average severity forms of alcoholic intoxications. The duration of hospitalization of patients with acute intoxications with cauterizing poisons of different degrees of severity is significantly decreased. The implementation of new diagnostic and curative technologies, standards and algorithms of medical care and extension of bed stock of department of acute intoxications permitted in general to decrease average period of hospitalization of patients in 2013 as compared with 2006.

The article deals with the results of examination and treatment of 37 patients with hemophiliac arthropathies of knee joints being observed in department of restorative ortho-surgery and poly-trauma of the Republican research center of emergency medical care (Astana, Kazakhstan) during 2010-2013. The organization of highly specialized medical care to patients with hemophilia with active implementation of early surgical rehabilitation of affected joint in complex treatment facilitated increasing of number of positive results at the expense of recovering of quality of life of patients. The excellent anatomical functional results are obtained in 26.7%, good results in 51.1% and satisfactory results in 22.2% of patients. There were no unsatisfactory outcomes of treatment.

The monitoring of patients with ovary cancer was implemented to evaluate effect of combined treatment the content of haptoglobin (the immunoturbidimetric technique applied) and oxydase activity of ceruloplasmin (the colorimetric technique applied). The comparison of obtained data with results of ultrasound monitoring and parameters of intratumoral hemodynamics of local recurrence was implemented. The reliable alterations of examined indicators were established under appearance of recurrence of ovary cancer and intensification of vascularization of recurrent tumor. The study established increased content of haptoglobin in patients with remission (as compared with its level in group of healthy women) and its significant increasing under expressed vascularization of recurrent tumor. The dynamics of level of haptoglobin corresponded to dynamics of ultrasound parameters of evaluation of effectiveness of treatment of recurrence. The alteration of ceruloplasmin activity was less expressed though it was detected at the earlier stage of recurrence in patients with avascular recurrence.

The epidemiological surveillance of enterovirus infections is an actual issue of health care in many countries and provides organization of control at different levels. The study was organized to examine particular characteristics of enterovirus infection at social ecosystem, cellular and sub-cellular levels. During 2010-2012 the fecal suspensions from 121 children and 127 adults were analyzed. The serological, virological and molecular genetic methods were applied. The following marker characteristics of enterovirus were examined: characteristics of miotropism, cytopathic effect, s, d and rct 40. The rate of occurrence of enterovirus infection in different age groups was established: 0-6 months - 22%, 7-11 mouths - 41.1%, 1-2 years - 39%, 2-14 years - 19%. The serotype-specific landscape of isolated enteroviruses was as follows: Coxsackie A types 17, 18, 20 and 21. It is demonstrated that express diagnostic of enterovirus infection requires applying indication of RNA enterovirus in different bio-samples simultaneously. It is established that cultural and serological methods are rather important for retrospective epidemiological analysis of enterovirus infection.

The malignant neoplasms are quite often combined with psychic disorders of depressive and anxiety spectrum which aggravate course and prognosis of main disease. The article considers issues related to detection of comorbide emotional disorders in patients with cancer. The diagnostic value of psychometric techniques of evaluation of symptoms of anxiety and depression and data concerning of effectiveness and safety of pharmaceutical agents applied in oncological practice are analyzed. The results of implementation of techniques of psychotherapeutic intervention in complex treatment of patients with oncological pathology are presented. The conclusion is made that further development of actual issues of diagnostic, therapy and prevention of anxiety and depressive conditions in patients with cancer require integration of scientific and practical activities of oncologists, psychiatrists and psychotherapists.