Vol 23, No 3 (2017)

Articles
THE DYNAMICS OF APPLICATION OF ANTI-THROMBOTIC IN PATIENTS FIBRILLATION OF ATRIUMS: ORIGINAL DATA AND REVIEW OF NATIONAL REGISTERS
Melehov A.V., Gendlin G.E., Dadashova E.F., Alekseeva E.M., Zaigraev I.A., Nikitin I.G.
Abstract
The article presents results of analysis of the register of out-patients and in-patients with atrium fibrillation (n=1624) observed in 2009-2015. The retrospective data analysis and prospective observation of certain percentage of patients were applied to evaluate rate and conformity of implementation of various groups of anti-thrombotic medications in conditions of real practice of polyclinics and hospitals of Moscow. The results are compared with data of national studies of this issue during recent years.
Medical Journal of the Russian Federation. 2017;23(3):116-126
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THE TACTIC OF CEMENTLESS TOTAL ENDOPROSTHESIS REPLACEMENT OF HIP JOINT IN PATIENTS WITH INHERENT HIP DISLOCATION
Yusupov K.S., Pavlenko N.N., Letov A.S., Sertakova A.V., Voskresenskiy O.Y., Anisimova E.A.
Abstract
Introduction. The total endoprosthesis replacement is a main method of treatment of congenital dislocation of hip. However, significant disorders of joint, resistant muscular contractures create technical complications under operation and force to apply various surgical tactics. Methods. The analysis was implemented concerning results of Crowe total endoprosthesis replacement in 69 patients with one-sided high hip dislocation type IV operated on the basis of traumatological orthopedic department of Saratovskii research institute of traumatology and orthopedics during 2010-2015. The treatment of patients was implemented using original genuine technique including total endoprosthesis replacement of hip joint combined with double V-subtrochanteric osteotomy. Results. The pathological types of implantation in operated hip joint are absent. On the whole, one can notice amelioration of bio-mechanical indices: cycle of step, period of double support, coefficient of rhythm. Among systemic complications of total endoprosthesis replacement one is to mark out phlebothrombosis established in 3 patients (7.1%) that was conditioned by sedentary state of patients. Among specific complications one stated dislocation related to inobservance of restrictive orthopedic regimen in 1 (2.4%) patient. None case of instability of prosthesis and difference in length of extremities in average periods of observation more than on 0.5 cm was established. This is a proof of effectiveness of developed technique of correcting V-subtrochanteric osteotomy. Therefore, the proposed technique of femoral bone osteotomy permitted to ameliorate the results of treatment and to diminish number of complications. The applied technique permits to obtain satisfactory clinical and technical results of surgical treatment of patients with high hip joint dislocation. The osteotomy permitted to eliminate difference in length of bones of patients and at that to ameliorate conditions for union of distal and proximal fragments of femur bone at the expense of larger surface of their contact.
Medical Journal of the Russian Federation. 2017;23(3):127-131
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THE FISHBURN METHOD AS A META-MATHEMATIC STATISTICAL APPROACH IN EVALUATION OF THE ROLE OF COMMON AND ATYPICAL AGENTS IN THE ETIOLOGIC STRUCTURE OF COMMUNITY-ACQUIRED PNEUMONIA IN ADULTS
Zhukova O.V., Brusnigina N.F., Kononova S.V., Speranskaya E.V., Efimov E.I.
Abstract
The actual guidelines on treatment of pneumonia emphasize necessity of establishment of etiologic diagnosis for therapy rationale. The necessity occurs to group agents according significance of their effect at evaluating etiologic role of a number of agents, for instance under implementation of epidemiological investigations, studying of etiologic structure of infections, planning of medicinal support. In that case, the Fishburn method fits perfectly. The purpose of study is to implement Fishburn method in establishing role of traditional and atypical agents in etiologic structure of community-acquired pneumonia.Materials and methods. The sampling included 172 examined patients aged from 18 to 30 years being under hospital treatment with confirmed diagnosis of community-acquired pneumonia. The analysis was applied to such biologic substrates as phlegm, blood, lavage (bronchoalveolar fluid). The technique of polymerase chain reaction was used. To determine weight coefficients of every analyzed etiologic agents with their subsequent distribution according percentage in etiologic structure. The Fishburn method was applied. The results. The main agents were established Streptococcus pneumoniae (separated in 86,3% of patients) and Haemophilus influenzae (41,2%). The mixed infection occurred in 65.8% of examined patients. The most propagated are such associations as Streptococcus pneumoniae and Haemophilus influenzae, Streptococcus pneumoniae and M. pneumoniae. Conclusion. S. pneumoniae, H. influenzae, M. pneumoniae are independent infection agents related to high and average levels. In the most cases, the detected agents were found in associations. A significant rate of detection of Herpes simplex I/II (16,2%) in blood and saliva of patients with community-acquired pneumonia testifies weakening of immune system. Herpes simplex I/II worsens course of diseases but is not considered as independent infection agent. The data obtained has epidemiological significance and can impact on development of medication support.
Medical Journal of the Russian Federation. 2017;23(3):132-136
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THE MENTAL HEALTH AND AGGRESSIVE BEHAVIOR OF WOMEN SERVING A SENTENCE IN CORRECTIONAL FACILITY
Shaklein K.N., Bardenshteyn L.M.
Abstract
The evaluation of status of mental health in women with hetero-aggressive, auto-aggressive behavior and without aggression was implemented on the basis of clinical examination of 1054 women serving a sentence in correctional facility. The results of study demonstrated that in women with aggressive behavior mental disorders of pre-clinical and clinical level occur reliably more often. In women with hetero-aggressive behavior organic and personality disorders prevail and in women with auto-aggressive behavior - neurosis-like and depressive disorders. The availability of mental manifestations effect aggressive behavior of women and its forms.
Medical Journal of the Russian Federation. 2017;23(3):137-141
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HE COMPLEX PROGRAM OF HEALTH IMPROVEMENT IN STUDENTS WITH DEADAPTATION DISORDERS
Artemenkov A.A.
Abstract
The complex program of health promotion for university students with disorders of adaptation processes was developed. The program includes application of dynamic, isometric and breathing exercises at working table during micro-pauses for amelioration of cerebral blood circulation. Increasing of resistance of organism to shortage of oxygen and normalization of vegetative functions. The application of massage of biologically active points applied during scheduled breaks is addressed to optimizing functional conditions of students. The implementation of complex of common developing exercises, application of health promoting running and rainy shower in the end of training exercise is oriented on increasing physical readiness and stimulating students' own adaptive possibilities.The approbation of originally developed program demonstrated its good efficiency in adjustment of deadaptation disorders occurring in the process of education. The results of study demonstrated that in boys and girls after three-months health promoting training neuro-psychic tension decreased, resistance to stress impact increased and anxiety lessened. Simultaneously, increasing of number of students with high level of adaptation to actual social conditions was observed. The amelioration of vegetative resistance of organisms of students was noted. The testing of physical readiness demonstrated that in students, after correcting exercises, muscular strength of wrists increased, velocity force capacities and indices of force endurance in control exercise "jump-rope" ameliorated and suppleness and static resistance of organism. The application of proposed means of health promotion promoted mobilization of workability of nervous cells and nervous system that is substantiated by the results of tapping-test.The application of health promotion program resulted in increasing of academic progress in studies of boys and girls up to 0.4-0.7 points. The obtained data was used to recommend for implementing in educational institutions the developed program of health promoting student youth and minimizing deadaptation disorders occurring in student social environment.
Medical Journal of the Russian Federation. 2017;23(3):142-147
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THE COMPARATIVE STUDYING OF ANTI-HYPOXEMIC ACTIVITY OF COMPLEX OF ZINC ACETATE WITH N-PROPARGYLIMIDAZOLE AND 3-HYDROXYPYRIDINE
Shakhmardanova S.A., Galenko-Yaroshevsky P.A., Parshina L.N., Trofimov B.A., Tarasov V.V., Maksimov M.L., Sologova S.S.
Abstract
The pharmacotherapy of hypoxia is an important task of modern experimental and clinical pharmacology. The medications with anti-hypoxic effect implemented into clinical practice unfortunately do not meet requirements of physicians due to poor efficiency, narrow range of active dosages and undesirable side effects. The complexes of zinc with N-alkenylimidazole demonstrated anti-hypoxic activity at various models of acute hypoxia within large range of dosage. Therefore, further studying of zinc-contained compounds as possible correctors of hypoxia is of particular interest. The experiments with white nonlinear male mice were used for comparative investigation of ant-hypoxic effect of complex compounds of zinc acetate with N-propargylimidazole and 3-hydroxipyridine, including complexes immobilized on sulfated arabinogalaсtan and also well-known anti-hypoxants and/or anti-oxidants: etomerzol, mexidol, nooglutil and hypoxen. It is demonstrated that anti-hypoxic effect of complex of zinc acetate with N-propargylimidazolein conditions of acute hypobaric hypoxia, acute hypoxia with hypercapnia acute hematic hypoxia by width of active dosages (1-100 mg/kg, intraperitoneally) and degree of expression (19-317% in comparison with control groups of animals) excels the similar effect in well-known anti-hypoxants and/or anti-oxidants: etomerzol (25-100 mg/kg, intraperitoneally), mexidol (100 mk per kg, intraperitoneally), nooglutil (25-100 mg/kg, intraperitoneally) and hypoxen (50-150 mg/kg, intraperitoneally). The protective effect of complex of zinc acetate with 3-hydroxipyridine by width of active dosages (25-100 mg/kg, intraperitoneally) and degree of expression (27-167% in comparison with control groups of animals) in conditions of exogenous hypoxia (acute hypobaric hypoxia and acute hypoxia with hypercapnia) excels similar effect of etomerzol and mexidol ans is comparable with effect of nooglutil and hypoxen. The complexes immobilized on sulfated arabinogalactan were ineffective.
Medical Journal of the Russian Federation. 2017;23(3):148-151
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THE RISK FACTORS OF DEVELOPMENT AND PROGRESSION OF CALCINED AORTIC STENOSIS
Andropova O.V., Alekseeva L.A., Minushkina L.O.
Abstract
The calcined aortic stenosis is one the most frequently occurring cardio-vascular diseases with unfavorable prognosis of course. The modern concepts about risk factors of development, pathogenesis and course of disease starting with inflammation and endothelial dysfunction and terminating with bone metaplasia permit determining prospective directions of deceleration of progression of calcined aortic stenosis. The high risk of unfavorable cardio-vascular occurrences associated with calcinosis of valvular apparatus of heart, availability of concomitant diseases making difficulties for correction of valvular impairments makes searching for causes of development and progression of ectopic calcification of aortic valve especially actual. The development of strategy of modification of risk factors and prevention of progression of early valvular impairments and blood circulation insufficiency are actual to the same extent. The review considers main clinical factors associated with development of calcined aortic stenosis, significance of genetic polymorphism in development of this heart disease and also main pathogenic mechanisms of its progressing.
Medical Journal of the Russian Federation. 2017;23(3):152-157
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The possibility of development of hypomagnesemia of surgical patients
Sviridov S.V., Vedenina I.V., Kochergin V.G.
Abstract
The modern diagnostic and correction of disorders of water-electrolytic balance plays a most important role on stages of treatment of surgical patients. Many patients are accepted into hospital already with expressed disorders of content of such cations as potassium, sodium, calcium. Especially is expected outbalance of electrolytes in patients with acute abdominal pathology - peritonitis, intestinal obstruction, acute pancreatitis, etc. At the same time, disorders of water-electrolytic balance in surgical patients can be conditioned not only by main surgical pathology. One is to consider presence of number of concomitant diseases of cardio-vascular system, kidneys, endocrine glands, gastrointestinal tract and also prolonged intake of various groups of medications. The article analyzes various aspects of development of hypomagnesemia during perioperational period in surgical patients. The importance of dynamic control of level of Magnesium (Mg2+) in blood plasma is established.
Medical Journal of the Russian Federation. 2017;23(3):158-164
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THE FLAT FOOT OF CHILDREN AGE: ACTUAL STATE OF PROBLEM
Timaev M.K., Sertakova A.V., Kurkin S.A., Rubashkin S.A.
Abstract
More than 90% of all visits to children orthopedist is related to pathology of feet of children age, flat foot in particular. The review present actual data concerning classification, etiology and characteristics of pathological anatomy of disease, diagnostic techniques and features of gait. The data related to present methods of conservative and operational treatment of flat foot is presented.
Medical Journal of the Russian Federation. 2017;23(3):165-168
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