Email this article TOXICITY UNDER A SINGLE INTRAGASTRIC ADMINISTRATION OF THE ACTIVE CLATHRATE COMPLEX OF β-CYCLODEXTRIN WITH 3-(2-PHENYLETHYL)-2-THIOXO-1,3- THIAZOLIDIN-4-ONE
- Authors: Erimbetov K.T.1,2, Zemlyanoy R.A.1, Bondarenko E.K.2, Goncharova A.Y.2
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Affiliations:
- All-Russian Research Institute of Physiology, Biochemistry and Animal Nutrition - a branch of the Federal Science Center of Animal Husbandry named after academician L.K. Ernst
- Research Center «Park of Active Molecules»
- Issue: No 6 (2020)
- Pages: 59-62
- Section: New information on toxicity and hazard of chemical and biological substances
- Published: 04.01.2021
- URL: https://journals.eco-vector.com/0869-7922/article/view/641270
- DOI: https://doi.org/10.36946/0869-7922-2020-6-59-62
- ID: 641270
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Abstract
The clathrate complex of 3-(2-phenylethyl)-2-thioxo-1,3-thiazolidin-4-one with β-cyclodextrin in the form of a nanopowder with an average particle size of 40.5 nm, with a wide range of pharmacological properties, was developed for the first time. It belongs to class VI of relatively harmless drugs according to Hodge and to class 5 in accordance with GOST 32644-2014.
About the authors
K. T. Erimbetov
All-Russian Research Institute of Physiology, Biochemistry and Animal Nutrition - a branch of the Federal Science Center of Animal Husbandry named after academician L.K. Ernst; Research Center «Park of Active Molecules»
Author for correspondence.
Email: erimbetovkt@mail.ru
Erimbetov Kenes Tagaevich
249013, Kaluga Region
Russian FederationR. A. Zemlyanoy
All-Russian Research Institute of Physiology, Biochemistry and Animal Nutrition - a branch of the Federal Science Center of Animal Husbandry named after academician L.K. Ernst
Zemlyanoy Ruslan Alexandrovich
249013, Kaluga Region
Russian FederationE. K. Bondarenko
Research Center «Park of Active Molecules»
Email: bondarenko@pam-alliance.ru
Bondarenko Ekaterina Valer’evna
Obninsk, Kaluga region
Russian FederationA. Ya. Goncharova
Research Center «Park of Active Molecules»
Email: goncharova@pam-alliance.ru
Goncharova Anna Yakovlevna
Obninsk, Kaluga region
Russian FederationReferences
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