REVIEW OF RESULTS OF DOUBLE BLIND PLACEBO-CONTROLLED STUDY OF PHASE III CLADRIBINE IN TABLETS FOR TREATING MULTIPLE SCLEROSIS - CLARITY



Cite item

Full Text

Abstract

There was presented a review of foreign publications of 2009 about the investigation results of clinical effectiveness of Cladribine (in tablets) for treating Multiple Sclerosis.

About the authors

Tatyana Valerjevna Sidorenko

Russian State Medical University

Email: t.v.sidorenko@rambler.ru
кафедра неврологии и нейрохирургии лечебного факультета на базе ГКБ №1; Российский государственный медицинский университет; Russian State Medical University

References

  1. Comi, G. Reduction in MRI activity in relapsing-remitting multiple sclerosis achieved with cladribine tablets in the 96-week, Phase III, double-blind, placebo-controlled CLARITY study / G. Comi, S. Cook, G. Giovannoni et al. //Multiple Sclerosis. - Vol. 15, suppl.2. - S. 136.
  2. Cook, S. Safety and tolerability of short-course oral treatment with cladribine tablets for relapsing-remitting multiple sclerosis (RRMS) in the 96-week, phase III, double-blind, placebo-controlled CLARITY study / S. Cook, P. Vermersch, G.Comi et al. // Journal of the neurological sciences. - Vol. 285, suppl.1. - S. 206.
  3. Giovannoni, G. Disease activity-free results for cladribine tablets in the 96-week, Phase III, double-blind, placebo-controlled CLARITY study in patients with relapsing-remitting multiple sclerosis / G. Giovannoni, G. Comi, S. Cook et al. // Multiple Sclerosis. - Vol. 15, suppl. 2. - S. 137.
  4. Giovanonni G. Clinical outcomes with cladribine tablets in the 96-week, phase III, double-blind, placebo-controlled CLARITY study in patients with relapsing-remitting multiple sclerosis / G. Giovanonni, G. Comi, S. Cook et.al. // Multiple Sclerosis. - Vol. 15, suppl. 2. - S. 136-137.
  5. Leist, T.P. Mode of action (MoA) of cladribine tablets: activity in lymphocytes and implications for treatment of multiple sclerosis (MS) / T.P. Leist, M. Migliaccio, R. Weissert. // Journal of the neurological sciences. - Vol. 285, suppl.1. - S. 206-207.
  6. Miret, M. Evaluation of the long -term safety of cladribine tablets: design of a prospective 8-year safety registry / M. Miret, L. Perez-Gutthann, V. Viglietta et al. // Multiple Sclerosis. - Vol. 15, suppl. 2. - S. 239.
  7. Soelberg-Sшrensen, P. Effect of cladribine tablets on haematological profiles in patients with relapsing-remitting multiple sclerosis in the 96-week, Phase III, double-blind, placebo-controlled CLARITY study / P. Soelberg-Sшrensen, G. Comi, S. Cook et al. // Multiple Sclerosis. - Vol. 15, suppl. 2. - S. 137.
  8. Vermersch, P. Early onset of effects of treatment with cladribine tablets for relapsing-remitting multiple sclerosis in the 96-week, Phase III, double-blind, placebo-controlled CLARITY study / P. Vermersch, G. Comi, S. Cook et al. // Multiple Sclerosis. - Vol. 15, suppl. 2. - S. 249.
  9. Viglietta, V. Clinical development plan for cladribine tablets, an oral immunomodulator, for the treatment of multiple sclerosis / V. Viglietta, S. Greenberg, D. Mikol et al. // Multiple Sclerosis. Vol. 15, suppl. 2. - S. 126-127.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2010 Sidorenko T.V.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 75562 от 12 апреля 2019 года.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies