A CLINICAL CASE OF THE IDIOPATHIC SUPERFICIAL SIDEROSIS OF THE CENTRAL NERVOUS SYSTEM



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Abstract

There was presented a clinical case of a patient with superficial siderosis of the central nervous system. The presence of the clinical triad (sensorineural hearing loss, cerebellar ataxia, pyramidal symptoms), a progressive course of the disease and characteristic neuroimaging features (MRI in T2-gradient echo and SWI - Susceptibility-Weighted Imaging - MRI images, weighted by the inhomogeneity of the magnetic field) in the form of hemosiderin deposits has allowed to establish the diagnosis.

About the authors

Elena G Klocheva

North -West state medical I.I. Mechnikov University

department of neurology n.a. academician S.N. Davidenkov 195067, St.Petersburg, Piskarevsky pr., 47, 12 building

Vitaly V Goldobin

North -West state medical I.I. Mechnikov University

department of neurology n.a. academician S.N. Davidenkov 195067, St.Petersburg, Piskarevsky pr., 47, 12 building

Olga I Timonina

North -West state medical I.I. Mechnikov University

Email: o-timon@ya.ru
department of neurology n.a. academician S.N. Davidenkov 195067, St.Petersburg, Piskarevsky pr., 47, 12 building

References

  1. Fearnley J.M., Stevens J.M., Rudge P. et al. Superficial siderosis of the central nervous system // Brain. 1995. Vol. 118. P. 1051-1066.
  2. Huprikar N., Gossweiler M., Callaghan M., Bunge P. Agranulocytosis with deferiprone treatment of superficial siderosis // BMJ Case Rep. 2013. Aug. 7. 2013.
  3. Kumar N., Cohen-Gadol A.A., Wright R.A. et al. Superficial siderosis // Neurology. 2006. Vol. 66. P. 1144-1152.
  4. Kumar N. Superficial siderosis: association and therapeutic implication // Arch Neurol. 2007. Vol. 64. P. 491-496.
  5. Koppen A.H., Michael S.C., Li D. et al. The pathology of superficial siderosis of the central nervous system // Acta Neuropathol. 2008. Vol. 116. P. 371-382. Epub. 2008. Aug. 12.
  6. Leussink V.I., Flachenecker P., Brechtelsbauer D. et al. Superficial siderosis of the central nervous system: pathogenetic heterogeneity and therapeutic approaches // Acta Neurol. Scand. 2003. Vol. 107. P. 54-61.
  7. Linn J., Wollenweber F.A., Lummel N. et al. Superficial siderosis is a warning sign for future intracranial hemorrhage // J. Neurol. 2013. Vol. 260. P. 176-81.
  8. Messori A., Di Bella P., Herber N. et al. The importance of suspecting superficial siderosis of the central nervous system in clinical practice // Neurol Neurosurg Psychiatry. 2004. Vol. 75. P. 188-190.
  9. Pyhtinen J., Paakko E., Ilkko E. et al. Superficial siderosis in the central nervous system // Neuroradiology. 1995. Vol. 37. P. 127-128.
  10. Van Veluw S.J., Zwanenburg J.J., Engelen-Lee J. et al. In vivo detection of cerebral cortical microinfarcts with highresolution 7T MRI //J. Cereb. Blood Flow Metab. 2013. Vol. 33. P. 322-329.
  11. Wollenweber F.A., Buerger K., Mueller C. et al. Prevalence of cortical superficial siderosis in patients with cognitive impairment // J. Neurol. 2014. Vol. 261. P. 277-282.

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Copyright (c) 2015 Klocheva E.G., Goldobin V.V., Timonina O.I.

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