Incidence of depressive and anxiety disorders in COVID-19 patients

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Abstract

The aim of this study is to analyze the occurrence of depressive and anxiety disorders in patients with COVID-19 and to study the relationship of these disorders with organic damage to the central nervous system.

Material and methods. An analysis of occurrence of depressive and anxiety disorders in patients with COVID-19 was carried out at the infectious hospital of the KBGMU for the period June-August 2020. Depression and anxiety were identified using the Hospital Anxiety and Depression Scale (HADS) and compared with the MRI data of the brain. Statistical data processing was carried out using Microsoft Excel 7.0.

Results. According to the analysis, out of 76 patients with COVID-19, depressive disorders were observed in 36 (46.3%) patients, anxiety disorders — subclinical anxiety in 16 (21.05%), clinical anxiety — in 19 (25%). The absence of depressive disorders was observed in 40 (52.63%), the absence of anxiety — in 41 (53.94%). By gender differentiation of patients, depressive disorders in men — 20 (46.5%), women — 16 (48.48%). Anxiety disorders: subclinical anxiety in men — 11 (25.5%), women — 5 (15.15 %), clinical anxiety in men — 7 (16.2%), women — 12 (36.36%). The average age of patients at the time of the study was 45.7 years. When conducting MRI of brain, organic lesions were detected in 12 (16%) people, in 64 (84%) at the time of the study, organic lesions were not detected. When collecting a follow-up in 31 patients, depressive disorders were noted in 8 (25.8%), subclinical anxiety — 2 (6.45%), clinical anxiety — 2 (6.45%), no anxiety — 27 (87.09%), no depression — 23 (74.19%). No organic lesions were found at the time of MRI of brain.

Conclusion. When studying the occurrence of depressive and anxious states and their organic substrates, we found that there is no clear relationship between them and rather have a functional character.

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About the authors

Valentin N. Pavlov

Bashkir State Medical University

Email: Pavlov@bashgmu.ru
Russian Federation, 450008, Ufa, Lenin str., 3

Denis A. Karpov

Bashkir State Medical University

Author for correspondence.
Email: Karpovneuromd@gmail.com
ORCID iD: 0000-0001-9972-5746
Russian Federation, 450008, Ufa, Lenin str., 3

Shamil M. Safin

Bashkir State Medical University; Republican Clinical Hospital im. G.G. Kuvatova

Email: safinsh@mail.ru

Professor, Doctor of Medicine. Head of Special Medical Aid Centre - Neurosurgery

Russian Federation, 450008, Ufa, Lenin str., 3; 450005, Ufa, Dostoevsky str., 132

Vladimir L. Yuldashev

Bashkir State Medical University

Email: Uvlprof@gmail.com
Russian Federation, 450008, Ufa, Lenin str., 3

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Copyright (c) 2021 Pavlov V.N., Karpov D.A., Safin S.M., Yuldashev V.L.

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