Vol XLVI, No 2 (2014)

The activity of free-radical oxidation and expressiveness of clinical manifestation of disease (severity level) in children with spastic forms of children’s cerebral paralysis have been studied. It has been proved that in children with spastic diplegia of children’s cerebral paralysis and double hemiplegia with pathological changes of periventricular area the process of free-radical oxidation proceeds actively - the level of antiradical protection enzymes has been increased as well as products of lipid peroxidation. There was revealed a correlation of activity of oxidation processes and severity of clinical manifestations of children’s cerebral paralysis. It was established that a severe degree of the disease proceeds in the background of high-active peroxidation, especially of processes of lipid peroxidation.

On the basis of analysis of chemical (alcoholic) and processual (food, sex, shopping, internet addiction, work addiction) relationships there were shown common psychophysiological mechanisms of various forms of addictions. There was analyzed the role of addictive triggers activation of addictive realizations. There were described characteristics of addictive and pre-addictive person, which are not equal to the disorders of the psychotic level. It was stressed inadequacy of the psychopharmacological treatment of addictions, especially the use of neuroleptic drugs and harmful because of the absence of the target symptoms and general inhibitory effect on the motivations and creativity.

This review contains information on common approaches to the treatment of substance dependence in adolescents. Described the principles of treatment of substance dependence in adolescents in relation to clinical features and patterns of disease. Presented various forms of drug treatment adolescents due on the severity of the disease and the presence of comorbid psychiatric disorders. There were described the evidence-based methods in assisting adolescents: multidimensional family therapy, cognitive-behavioral therapy and motivational interviewing.

This article presents a review of publications of psychiatrists, philologists and literary critics, discussing the question of differential diagnosis of F.M. Dostoevsky disease. The way his illness was incorporated in his art during different periods of time was analyzed.

An intention of this study was to investigate the efficacy of «L-lysine aescinat» in complex treatment of acute and subacute low back pain, which arose as a neurological complication dorsopathies at the lumbar level. The study involved 50 patients who received standard therapy and 30 people also received «L-lysine aescinat». Patients in both groups showed similar significant positive clinical dynamics and improved quality of life to ten days of starting treatment. However, in the first group of patients indicators of usual daily activities, physical discomfort and rapid assessment of anxiety improved significantly faster on the fifth day (p <0, 01). «L- lysine aescinat» can provide more rapid reduction of pain, including potentiating the effects of other therapeutic medicines .

272 case histories were studied by archival method. All patients admitted for treatment for various forms of syphilis in the St. Petersburg dermatological clinic in the period from 2006 to 2011 inclusive. A significant frequency of adjustment disorders, addictive disorders and personality disorders were established in patients with syphilis and HIV. Most patients had risky behavior and poor social adjustment.

Data on structure of addictive pathology among the convicted persons in places of imprisonment in the Russian Federation are provided in the article. It is noted that there are more than 141,000 people with mental and substance abuse disorders in correctional facilities, of whom 62,700 have mental disorders, 56,400 were injecting drug users and 22, 600 patients with alcoholism. The system of obligatory and alternative treatment is analyzed. The conclusion about need of its improvement is drawn.

The results of experimental research of 120 individuals in state of alcohol dependence and without dependence are shown. The research showed that during alcohol dependence semantic signification of object-meaningful stimuli is provided by paradigmatic association which supports the processes of meaning construction towards dependence object. This tendency is specific for alcohol dependence and significantly different from the lack of dependence.

The article deals with the results of diagnostics of different aspects of deviant and addictive behavior, which includes using psychoactive substances, Internet-addiction and propensity to deviant behavior in juveniles with hearing disorders and in hard-of-hearing. Obtained results were compared with the level of respondents’ emotional intelligence.

On the example of professors A.U. Phreze, T.I. Yudin, and an associate professor S.V. Kurashov, combining work in the department of psychiatry of Kazan University with the management of the Kazan psychiatric hospital, the article shows a close connection of scientific and practical psychiatry in Kazan.