ACTIVITY OF FREE-RADICAL OXIDATION AT SMALL CHILDREN WITH SPASTIC FORMS OF CHILDREN’S CEREBRAL PARALYSIS AT EARLY RESIDUAL STAGE

The activity of free-radical oxidation and expressiveness of clinical manifestation of disease (severity level) in children with spastic forms of children’s cerebral paralysis have been studied. It has been proved that in children with spastic diplegia of children’s cerebral paralysis and double hemiplegia with pathological changes of periventricular area the process of free-radical oxidation proceeds actively - the level of antiradical protection enzymes has been increased as well as products of lipid peroxidation. There was revealed a correlation of activity of oxidation processes and severity of clinical manifestations of children’s cerebral paralysis. It was established that a severe degree of the disease proceeds in the background of high-active peroxidation, especially of processes of lipid peroxidation.

a children’s cerebral paralysis, periventricular leukomalacia, oxidative stress, severity level