Vol 16, No 5 (2013)

Articles
COMPARATIVE CHARACTERISTICS OF THERAPIES FOR CUTANEOUS BASAL-CELL CARCINOMA
Volgin V.N., Stranadko E.F., Trishkina O.V., Kabanova M.A., Kagoyants R.V.
Abstract
The results of comparative analysis of therapies for cutaneous basal-cell cancer suggest that photodynamic therapy (PDT) is the most effective method, extending significantly the armory of means used for the treatment of primary and relapsing cutaneous cancer, including cancer of inconvenient location (concha, corner of the eye, eye lids, nose, etc.) and for tumors resistant to previous traditional therapy. Photodynamic therapy can be used in complex with other therapeutic methods. The efficiency of PDT with different photosensitizers has been studied. By cosmetic results PDT is superior to other methods.
Russian Journal of Skin and Venereal Diseases. 2013;16(5):4-10
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CHRONIC URTICARIA AS AN AUTOIMMUNE DISEASE
Kolkhir P.V., Olisova O.Y., Kochergin N.G., Ignatyev D.V.
Abstract
The authors of this review of literature discuss the pathogenesis of autoimmune urticaria and the history of its distinguishing as a nosological entity. These data on autoimmune urticaria will be useful for specialists and will promote optimization of its diagnosis and therapy. Some autoimmune diseases can manifest by symptoms of chronic urticaria; on the other hand, urticaria is autoimmune in 30—40% cases. In addition, it is assumed that the disease is associated with the presence of autoantibodies — anti-FcεRI and (rarely) anti-IgE. It is essential to differentiate autoimmune urticaria from other disease forms by intradermal test with autoimmune serum and in vitro studies. It is characterized by a more severe prolonged course and resistance to antihistaminic therapy. In many cases the diagnosis of autoimmune urticaria allows dscontinuing further tests, aimed at detection of the disease cause.
Russian Journal of Skin and Venereal Diseases. 2013;16(5):10-16
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GARDNER-DIAMOND'S SYNDROME
Ivanov O.L., Teplyuk N.P., Pinegin V.B., Plieva L.R., Romanov D.V.
Abstract
The Gardner-Diamond syndrome in a female patient aged 40 is described. The syndrome was diagnosed by anamnesis, clinical picture, and positive intracutaneous test with suspension of patient’s own erythrocytes. Negative control was carried out. Blood clotting system parameters were normal.
Russian Journal of Skin and Venereal Diseases. 2013;16(5):17-22
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ON PHOTOPHERESIS EFFICIENCY IN ANETODERMIA
Molochkov V.A., Karzanov O.V., Prokofyev A.A., Molochkova Y.V.
Abstract
Extracorporeal photochemotherapy — photopheresis — was used for the treatment of anetodermia. A pronounced clinical effect (4 sessions every other day) was attained in the treatment of Schwenninger-Buzzi’a anetodermia (developing in the presence of Lewandowsky-Lutz verruciform epidermodysplasia) and Jadassohn ’s anetodermia. Photopheresis induced a trend to normalization of some immunological parameters. This is the first in world literature report about pronounced clinical efficiency and pathogenetic nature of photopheresis in anetodermia.
Russian Journal of Skin and Venereal Diseases. 2013;16(5):22-24
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TOXIC EPIDERMAL NECROLYSIS IN A CHILD
Albanova V.I., Brunova O.Y., Korsunsky A.A.
Abstract
Modern concepts on the etiology, pathogenesis, clinical manifestations, therapy, and prognosis of toxic epidermal necrolysis are presented. A clinical case in a girl aged 10 years is described; clinical course and treatment errors are discussed.
Russian Journal of Skin and Venereal Diseases. 2013;16(5):25-30
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THE ROLE OF NONINVASIVE METHODS IN STUDIES OF THE STRUCTURE AND FUNCTIONS OF NEWBORN SKIN
Shlivko I.L., Kamensky V.A., Donchenko E.V.
Abstract
The structure and functions of the skin were studied in the newborns by noninvasive methods. A comprehensive morphofunctional study was carried out in 10 newborns aged 1—28 days by optical coherent tomography using an optical coherent tomograph fitted with a flexible probe with a microscanner (wavelength 920 nm, longitudinal resolution 20 μ, transverse resolution 25 μ) and a multifunctional unit. The findings indicated that the skin of newborns differed by structure and functions from adolescent skin. The specific features of the newborn skin function were explained by its microstructure. The key differences in the structure, detected in the thick skin, demonstrated an incomplete process of skin structures formation by birth.
Russian Journal of Skin and Venereal Diseases. 2013;16(5):30-37
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RESTRICTIVE DERMATOPATHY: A RARE LETHAL HEREDITARY ABNORMALITY
Serdyukova E.A., Rodin A.Y., Franchuk M.E., Saprunova O.N.
Abstract
A rare case is presented: a lethal hereditary abnormality with autosomal recessive inheritance of restrictive dermatopathy, diagnosed in a preterm (week 29—30) girl, weighing 1140 g, with body length of 39 cm. The pathological complex included developmental abnormalities of the skin and its appendages, bone system, and polyorgan failure. The lethal outcome ensued on day 57 of life from bronchopulmonary dysplasia, aggravated by bilateral congenital polysegmented pneumonia in the presence of multiple lung atelectases and polyorgan (cardiovascular, cerebral) failure. Relevant publications (17 sources) are discussed and illustrations presented.
Russian Journal of Skin and Venereal Diseases. 2013;16(5):37-39
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CLINICAL AND MORPHOLOGICAL CHARACTERISTICS OF PIGMENTED LICHEN PLANUS
Snarskaya E.S., Proskurina M.V., Bobrov M.A., Molochkova Y.V.
Abstract
Clinical and morphological characteristics of a rare pigmented form of lichen planus are analyzed as exemplified by 4 cases observed by the authors. The observations demonstrate the clinical features of this form of lichen planus, difficult for the diagnosis and choice of therapy because of obscure etiology and manifestations similar to those of other skin diseases.
Russian Journal of Skin and Venereal Diseases. 2013;16(5):40-43
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LICHENOID REACTION OF THE SKIN PROVOKED BY TATTOO
Bakurov E.V.
Abstract
Probable complications associated with tattoos are discussed. Variants of skin reactions to color inks (inflammatory, granulomatous, lichenoid, infections, skin tumors) are presented. A clinical case is described: a girl aged 20 years developed a lichenoid reaction to the red pigment, similar to lichen planus, six months after tattooing.
Russian Journal of Skin and Venereal Diseases. 2013;16(5):43-46
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CLINICAL AND LABORATORY CHARACTERISTICS OF PSORIASIS ASSOCIATED WITH HORMONAL METABOLIC DISORDERS
Perlamutrov Y.N., Mikryukov A.V.
Abstract
Increasing incidence of severe forms of psoriasis with high incidence of comorbidities necessitates special attention to the dermatosis course in patients with excessive body weight and obesity. Our study detected significant differences in the course of psoriasis in patients with different body weight indexes. Characteristic hormonal metabolic disorders and disorders in the food behavior and quality of life were detected in patients with excessive body weight and obesity in comparison with the group of psoriasis patients with normal body weight index.
Russian Journal of Skin and Venereal Diseases. 2013;16(5):46-50
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TRICHOTILLOMANIA
Albanova V.I.
Abstract
Patients with some primary mental disorders (trichotillomania, onichotillomania, onichophagia, neurotic excoriations, dermatozoic delirium) frequently consult a dermatologist. The task of the dermatologist is to diagnose the disease and to persuade the patient to consult a psychiatrist. Two cases with trichotillomania are described: a girl aged 16 years with involvement of the hairy part of the head and a little girl aged 6 years with eyebrows and eyelids involvement. The causes of disease, age-associated clinical symptoms, and most informative diagnostic methods (trichoscopy, trichogram, microscopic examination of the hairs) are discussed. The basic therapeutic methods used in psychiatry, prognosis, and disease course are described.
Russian Journal of Skin and Venereal Diseases. 2013;16(5):50-54
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DIAGNOSTIC SIGNIFICANCE OF OSTEOCALCIN IN LEPROUS OSTEODESTRUCTIVE COMPLICATIONS
Degtyarev O.V., Sazykina U.A., Lazareva E.N.
Abstract
Osteocalcin protein was measured in leprous patients with osteodestructive complications and in the reference group of patients with other diseases. Osteocalcin concentrations were higher than normally in both groups, but to a different degree. The concentrations of this protein were significantly higher in leprous patients with osteodestructive changes. A 10-fold elevation of serum osteocalcin concentrations indicated destructive changes in bone tissue.
Russian Journal of Skin and Venereal Diseases. 2013;16(5):54-56
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TACROLIMUS IN THE TREATMENT OF DIFFERENT SKIN DISEASES
Olisova O.Y., Kochergin N.G., Murakhovskaya E.K., Keskin G.M., Olisov A.O., Davidovich M.I., Garanyan L.G., Shurubei V.A.
Abstract
Tacrolimus, a new calcineurin inhibitor, was used for topical therapy of skin diseases. Characteristics of the drug are presented, the mechanism of its action is described. The efficiency of tacrolimus is demonstrated by published data and the authors’ experiance. Tacrolimus was effective in the treatment of atopic dermatitis, its efficiency was comparable to that of topical corticosteroids. Tacrolimus was also effective in psoriasis, vitiligo, rosacea, and seborrheic dermatitis.
Russian Journal of Skin and Venereal Diseases. 2013;16(5):57-61
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HIGH CONCENTRATION OF 3β-HYDROXYSTEROID DEHYDROGENASE IN SKIN CELLS OF PATIENTS WITH ACNE VULGARIS
Bagrets A.N., Kuznetsov V.A., Ruksha T.G.
Abstract
The synthesis of testosterone is catalyzed by 3β-hydroxysteroid dehydrogenase. The development of acne is partialy associated with androgen-mediated hyperplasia of the sebaceous glands. The distribution and concentrations of 3β-hydroxysteroid dehydrogenase in the skin were studied in patients with acne. The results indicated hyperexpression of 3β-hydroxysteroid dehydrogenase in sebocytes, this presumably indicating disorders of the steroid metabolism in acne skin.
Russian Journal of Skin and Venereal Diseases. 2013;16(5):62-64
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The mystery of William Hogarth
Monakhov S.A.
Russian Journal of Skin and Venereal Diseases. 2013;16(5):65-65
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Single ring-shaped tumor on the skin of the temple
Khlebnikova A.N., Bobrov M.A., Shuginina O.I.
Russian Journal of Skin and Venereal Diseases. 2013;16(5):67-67
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