Vol 13, No 5 (2010)

Articles
Fotodinamicheskaya terapiya aktinicheskogo keratoza s applikatsionnym primeneniem "Fotoditazina"
Sukhova T.E., Molochkov V.A., Romanko Y.S., Changlyan K.A., Tret'yakova E.I.
Abstract
The paper describes the currently available treatment for actinic keratosis (AC). The authors treated 20 patients with AC by photodynamic therapy with application of the photosensitizer Photoditasine. A total of 115 lesion foci were treated. The efficiency of the technique after 2-month therapy was 93.9%. Recurrences were noted in 2 foci in 2 months 1.5 and 2 years after treated (1.7%). The efficiency during less than 2-year follow-up was 92.2%.
Russian Journal of Skin and Venereal Diseases. 2010;13(5):4-8
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Sluchay sochetaniya mnozhestvennogo pyatnistogo nevusa s psoriazom
Molochkov V.A., Bagapsh L.S., Novoselova N.V.
Abstract
The paper reports a case of multiple nevus spilus (two foci on the back and shoulder) concurrent with type 1 psoriasis in a 22-year-old woman.
Russian Journal of Skin and Venereal Diseases. 2010;13(5):8-9
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Lokalizovannyy follikulyarnyy mutsinoz
Kryazheva S.S., Snarskaya E.S., Belova N.I., Bobrov M.A.
Abstract
The authors review the literature (24 Russian and foreign references) and their case of follicular mucinosis. They discuss the specific features of different types of follicular mucinosis and their case of the benign type of the disease developing as a process located on the forearm in a patient suffering from ovarian polycystosis and lichen pilaris.
Russian Journal of Skin and Venereal Diseases. 2010;13(5):10-12
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Osobennosti tsitokinspetsificheskogo autoimmuniteta pri piodermiyakh
Volkova E.N., Morozov S.G., Lange D.A., Il'in L.A.
Abstract
The paper gives new information on the immunopathogenesis of pyoderma of various etiologies. Imbalance has been found in the system of idiotypic and antiidiotypic antibodies to interferon-γ and antiidiotypic antibodies. Their level and ratio are shown to correlate with the severity and duration of pyoderma.
Russian Journal of Skin and Venereal Diseases. 2010;13(5):12-16
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Sifilidopodobnoe impetigo u rebenka s enkoprezom, razvivshimsya posle proktoplastiki po povodu vrozhdennoy atrezii pryamoy kishki
Bazaev V.T., Tseboeva M.B., Tsarueva M.S., Belikova Z.X.
Abstract
The paper describes papulous syphilid-like impetigo in a child with encopresis that has developed after proctoplasty for congenital rectal atresia. Continuous fecal leakage, maceration maintain the chronic course of the process and reduce the benefit of the therapy performed. The case is of interest as an example of differential diagnosis with the manifestations of secondary recurrent syphilis.
Russian Journal of Skin and Venereal Diseases. 2010;13(5):16-17
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Inversnye ugri: nekotorye aspekty patogeneza, diagnostiki i lecheniya
Mikheev G.N., Araviyskaya E.R., Sokolovskiy E.V., Kholodilova N.A.
Abstract
The paper reviews an update on the pathogenesis and clinical features of acne inverse. It describes the authors' cases of this rare and severe form of acne. The problems of the timely diagnosis and efficient treatment of this pathology are discussed.
Russian Journal of Skin and Venereal Diseases. 2010;13(5):18-23
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Kamera Raykha v terapii khronicheskikh dermatozov
Tret'yakova E.I., Kiselev S.O., Groznova A.A.
Abstract
The paper considers the effect of Reich's chamber in therapy for various dermatoses. Ninety-two patients received traditional treatment for major diseases and a course of procedures in Reich's chamber. The course of therapy was 8-13 sessions; the duration of each procedure was 30 minutes. The chamber had positive and none effects in 90 (97.7%) and 2 (2.3%) of the patients, respectively. Reich's chamber treatment went well and was supplemented by conventional procedures and treatments for chronic dermatoses, it showed a high physiological nature and a comprehensive action on the body and substantially enhanced the effect of conventional treatment
Russian Journal of Skin and Venereal Diseases. 2010;13(5):23-26
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Eritrodermiya pri toksokaroze
Ovsyannikova G.V., Molochkov V.A., Pelepets L.P., Fedorovskaya A.V.
Abstract
The paper first describes a case of secondary erythroderma occurring in the parasitic disease. The differential diagnosis of different forms of erythroderma should consider the following factors: age, a history of dermatoses, use of drugs, and parasitic infestation. Since erythroderma may rapidly develop in lymphoproliferative diseases, the efficiency of differential diagnosis of erythrodermic skin lesions in cutaneous T-cell lymphoma is analyzed and the current treatment regimen for skin lesions in toxocarosis given. The findings suggest the high efficiency of treatment.
Russian Journal of Skin and Venereal Diseases. 2010;13(5):26-30
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Sluchay krasnogo otrubevidnogo volosyanogo lishaya, imitiruyushchego psoriaz, u bol'noy sakharnym diabetom
Kryazheva S.S., Galustyan M.A.
Abstract
The paper describes the acute onset of pityriasis rubra pilaris mimicking psoriasis in a 70-year-old female patient with type 2 diabetes mellitus. A rapid eruption regression was achieved by multimodality therapy including neotigazon. Differential diagnosis of the condition and psoriasi was made.
Russian Journal of Skin and Venereal Diseases. 2010;13(5):30-32
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Infektsiya virusa gepatita S i pozdnyaya kozhnaya porfiriya v regionakh Vostochnoy i Zapadnoy Sibiri (kliniko-statisticheskoe issledovanie)
Krivosheev B.N., Kuznetsova N.P., Chashchin A.Y., Krivosheev A.B., Kondratova M.A.
Abstract
One hundred and seven patients (99 males and 8 women) aged 30-68 years (mean age 49.3±2.3 years) with porphyria cutanea tarda (PCT) identical in main clinical and statistical indicators were examined in 2 administrative areas of the Siberian Region (Irkutsk and Novosibirsk Regions) during 12 years (1998-2009). Enzyme immunoassay revealed a total of hepatitis C virus antibodies in 47 (43.9%) patients, including 12 (44.4±9.7%) of 27 patients from the Irkutsk Region and 35 (43.8±5.5%) of 80 patients from the Novosibirsk Region) (p > 0.5). Polymerase chain reaction found hepatitis C virus (HCV) RNA (viral load 105-106 copies/ml) in virtually all the examinees, which was indicative of the active course of infection at the stage of HCV replication. Genotyping indicated that HCV genotype 1b was dominant (91.3%) in the Siberian Region of Russia, as in other countries of the Eurasian and American continents, whereas genotype 3a was less frequently recorded (8.7%). Differential assessment of the dermatologic syndrome PCT, the age periods of manifestations of the disease, the specific features of its seasonal course, and daily urinary porphyrin excretion demonstrated that there were no great differences in patients with HCV infection versus those without viral hepatic lesion. However, hepatic dysfunctions were significantly more frequently detectable when PCT was concurrent with HCV infection, which was naturally attended by enhanced transaminase activities and higher iron levels in the serum. HCV plays an important etiological role in PCT and should be considered in this disease as a trigger, the porphyrinogenic effect of which is shown in combination with other risk factors (chronic alcohol intoxication, iron overload syndrome).
Russian Journal of Skin and Venereal Diseases. 2010;13(5):33-41
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Immunogistokhimicheskie osobennosti ochagov atrofodermii Pazini-P'erini
Romanenko K.V.
Abstract
Markers, such as CD3, CD8, CD20, CD79α, CD68, CD1α, CD34, CD105, αSMA, vimentin, eNOS, Ki67, collagen IV, bcl2, and caspase 3, were studied to reveal the immunohistochemical features of the derma and epidermis in atrophoderma of Pasini-Pierini. In the latter, inflammatory changes as dermal infiltration mainly by CD20+ and CD68+ cells were found to be followed by fibrous rearrangements. The latter (if judged from the dermal dendrocytes (elevated levels of αSMA+ and vimentin-positive dendrocytes and decreased CD34+ cell counts), their ability to synthesize endoglin, lower eNOS levels, and higher caspase 3 concentrations) have common mechanisms with those in scleroderma and lichen scleroatrophicus.
Russian Journal of Skin and Venereal Diseases. 2010;13(5):41-43
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Sluchay vrozhdennogo polikeratoza Turena
Fal'ko E.V., Shabel'skaya V.V., Gubich E.S.
Abstract
The authors describe the rare hereditary disease Touraine's congenital polykeratosis and give the data available in the literature and their observation of this dermatosis in a 14-year-old girl.
Russian Journal of Skin and Venereal Diseases. 2010;13(5):43-45
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Eksperimental'naya identifikatsiya komponentov OKT-izobrazheniy nogtevogo apparata
Petrova G.A., Firsova M.S., Shlivko I.L., Chekalkina O.E., Zor'kina M.V., Petrova K.S.
Abstract
The paper presents the results of in vivo and ex vivo experiments, which suggest that optical coherence tomography enables the major anatomic components of the nail apparatus (nail wall, nail plate, nail bed, matrix, eponychium, hyponychium, free edge) to be visualized in lifetime and it may be proposed for diagnosis as an morphological method for examining the nail apparatus as an alternative to biopsy.
Russian Journal of Skin and Venereal Diseases. 2010;13(5):45-48
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Sluchay zlokachestvennogo techeniya vtorichnogo sifilisa u bol'nogo, stradayushchego narkomaniey
Grebenyuk V.N., Olisov A.O., Kuleshov A.N., Komlev M.V.
Abstract
The paper describes a case of the malignant course of a secondary syphilis period. It provides the clinical characteristics of the infection and patient management tactics.
Russian Journal of Skin and Venereal Diseases. 2010;13(5):48-50
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Sravnitel'naya otsenka informativnosti metodov laboratornoy diagnostiki trikhomoniaza u muzhchin
Mavzyutov A.R., Mustafina G.R., Nikonorov Y.M., Khismatullina Z.R.
Abstract
Direct methods for laboratory detection of Trichomonas vaginalis in urogenital trichomoniasis (UT) were comparative analyzed. Polymerase chain reaction (PCR) showed the highest sensitivity and specificity irrespective of the topic (urethritis, urethroprostatitis) and the duration of male UT and the intensity of inflammation. Moreover, the values of the prognostic value of negative and positive results may serve as main criteria for developing new diagnostic test systems for UT.
Russian Journal of Skin and Venereal Diseases. 2010;13(5):51-54
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Mestnaya immunoterapiya kandidoznykh vul'vovaginitov
Snimshchikova I.A., Il'ina O.V., Khalilov M.A., Vislobokov A.V.
Abstract
The study was undertaken to optimize therapy for vulvovaginal candidiasis in the presence of chronic inflammatory diseases of small pelvic organs, by topically using immunoregulatory peptides (myelopide, superlymph). Local immunotherapy with these agents was shown to be promising in multimodality treatment programs for vulvovaginal candidiasis in the presence of chronic inflammatory diseases of small pelvic organs.
Russian Journal of Skin and Venereal Diseases. 2010;13(5):54-56
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Zagadka Modil'yani
Monakhov S.A.
Russian Journal of Skin and Venereal Diseases. 2010;13(5):56-56
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Eritema, voznikshaya na meste ukusa kleshcha
Belousova T.A., Teplyuk N.P., Osipova K.V.
Russian Journal of Skin and Venereal Diseases. 2010;13(5):56a-56a
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