Penis-saving treatment of penile cancer


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Abstract

Conservative penis-salvage treatment provides a complete local
effect in 55% cases, preservation of the penis in 51.4% patients without
a fall in long-term specific and recurrence-free survival compared
to penectomy and can be recommended as an alternative to penis amputation
in patients with stages Tis-T2. Removal of a penile tumor
raises efficacy of salvage treatment and insignificantly increases survival.
Application of surgical treatment only is associated with a high
rate of local recurrences. Chemoradiotherapy in penile cancer is significantly
more effective vs each method alone. Radiation in a total
focal dose more than 60Gy improves local control over the tumor.
Most effective are schemes of chemotherapy based on bleomycin.
Polychemotherapy has no advantages over monochemotherapy with
bleomycine.

References

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