An expandedtechnique of transrectal prostatic biopsy
- 作者: Pushkar DY.1, Govorov AV1, Bernikov AN1
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隶属关系:
- 期: 编号 2 (2004)
- 页面: 31-33
- 栏目: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/275045
- ID: 275045
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To compare diagnostic value of transrectal prostatic biopsy in obtaining
samples of tissue from different sites in patients with various
levels of prostate-specific antigen (PSA) and prostate size, we made
primary transrectal biopsy of the prostate in 486 patients. The patients
were divided into 7 groups by the number of punctures at biopsy (from
6 to 18). Among the patients with PSA under 20 ng/ml in the number
of tissue biopsy samples 18, a rise in prostatic cancer detection rate
(PCDR) was 16.6%. In PSA above 20 ng/ml, a statistically significant
maximal rise in PCDR occurred in the increase of biopsy number
from 6 to 12 (by 9.3%). The number of local cancer forms in patients
with PSA < 20 ng/ml among all the detected cases rose from 70%
(biopsy from 6 sites) to 92.3% (biopsy from 18 sites). Among the patients with
PSA < 20 ng/ml and the size of the prostate > 50 sm3, a
significant rise of PCDR increased from 20 to 33.3% in an increase
of the puncture number from 6 to 12. In the group of patients with
the same PSA level and prostate > 50 cm3 PCDR improves in biopsy
from 14, 16 and 18 sites (from 12.1 to 27.7%, 28.5 to 33.3%, respectively).
Standard biopsy is insufficient for adequate PCDR, it is necessary
to obtain samples of tissue from a large number of sites with
puncture of peripheral zone of the prostate. Transrectal biopsy of the
prostate according to the extended method improves PCDR, primarily,
in local cancer.
samples of tissue from different sites in patients with various
levels of prostate-specific antigen (PSA) and prostate size, we made
primary transrectal biopsy of the prostate in 486 patients. The patients
were divided into 7 groups by the number of punctures at biopsy (from
6 to 18). Among the patients with PSA under 20 ng/ml in the number
of tissue biopsy samples 18, a rise in prostatic cancer detection rate
(PCDR) was 16.6%. In PSA above 20 ng/ml, a statistically significant
maximal rise in PCDR occurred in the increase of biopsy number
from 6 to 12 (by 9.3%). The number of local cancer forms in patients
with PSA < 20 ng/ml among all the detected cases rose from 70%
(biopsy from 6 sites) to 92.3% (biopsy from 18 sites). Among the patients with
PSA < 20 ng/ml and the size of the prostate > 50 sm3, a
significant rise of PCDR increased from 20 to 33.3% in an increase
of the puncture number from 6 to 12. In the group of patients with
the same PSA level and prostate > 50 cm3 PCDR improves in biopsy
from 14, 16 and 18 sites (from 12.1 to 27.7%, 28.5 to 33.3%, respectively).
Standard biopsy is insufficient for adequate PCDR, it is necessary
to obtain samples of tissue from a large number of sites with
puncture of peripheral zone of the prostate. Transrectal biopsy of the
prostate according to the extended method improves PCDR, primarily,
in local cancer.
参考
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- Hodge К. К., McNeal J. E., Terris М. К. et al. Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate. J. Urol. (Baltimore) 1989; 142: 71-74.
- Karakiewicz P. I., Bazinet M., Aprikian A. G. et al. Outcome of sextant biopsy according to gland volume. Urology 1997; 49: 55-59.
- Vashi A. R., Wojno K. J., Gillespie B. et al. A model for the number of cores per prostate biopsy based on patient age and prostate gland volume. J. Urol. (Baltimore) 1998; 159: 920- 924.
- Presti J. C. Systematic biopsy of the prostate: 6 just isn't enough. Contemp. Urol. 1999; Dec: 11-18.
- Uzzo R. G., Wei J. Т., Waldbaum R. S. et al. The influence of prostate size on cancer detection. Urology 1995; 46: 831-836.
- Chang J. J., Shinohara K., Bhargava V. et al. Prospective evaluation of systematic sextant transition zone biopsies in large prostates for cancer detection. J. Urol. (Baltimore) 1998; 160: 2111-2115.
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