MR imaging in diagnosis of localized prostatic cancer
- Authors: Shatov AV1, Ognerubov NA1
-
Affiliations:
- Issue: No 3 (2004)
- Pages: 25-30
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/275250
- ID: 275250
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Abstract
To evaluate efficacy of MR imaging (MRI) in diagnosis of local
prostatic cancer (LPC) and validity of MRI performance in patients
with high levels of prostate-specific antigens (PSA), we made a retrospective
analysis of a combined examination of 210 patients including
MRI (100%). Of them, 68 (32.4%) had prostatic cancer (LPC
pTl-pT2 in 27 patients, 39.7%), 87 (41.4%) had benign prostatic hyperplasia
(BPH) and 35 (16.7%) - chronic prostatitis (CP). 17
(8.1%) patients were free of prostatic diseases. MRI accuracy in diagnosis
of LPC was 60%, sensitivity 70%, specificity 54%, in positive
and negative prognostic values 50 and 73%, respectively. Some features
of LPC were seen in MRI of BPH, CP and control patients.
MRI symptoms characteristic for one of the above diseases only were
not determined. We believe that MRI is indicated in suspected prostatic
cancer located in the central zone and anterior lateral regions
of the peripheral zone (impalpable prostatic cancer). Prostatic MRI
with assessment of the lower spine and pelvic bones is justified in men
over 50 years if PSA is above 10 ng/ml. Early and accurate diagnosis
of LPC by MRI is impossible without evaluation of clinical and PSA
data.
prostatic cancer (LPC) and validity of MRI performance in patients
with high levels of prostate-specific antigens (PSA), we made a retrospective
analysis of a combined examination of 210 patients including
MRI (100%). Of them, 68 (32.4%) had prostatic cancer (LPC
pTl-pT2 in 27 patients, 39.7%), 87 (41.4%) had benign prostatic hyperplasia
(BPH) and 35 (16.7%) - chronic prostatitis (CP). 17
(8.1%) patients were free of prostatic diseases. MRI accuracy in diagnosis
of LPC was 60%, sensitivity 70%, specificity 54%, in positive
and negative prognostic values 50 and 73%, respectively. Some features
of LPC were seen in MRI of BPH, CP and control patients.
MRI symptoms characteristic for one of the above diseases only were
not determined. We believe that MRI is indicated in suspected prostatic
cancer located in the central zone and anterior lateral regions
of the peripheral zone (impalpable prostatic cancer). Prostatic MRI
with assessment of the lower spine and pelvic bones is justified in men
over 50 years if PSA is above 10 ng/ml. Early and accurate diagnosis
of LPC by MRI is impossible without evaluation of clinical and PSA
data.
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