Use of low-molecular heparins in prevention and treatment of thrombotic complications after radical prostatectomy
- Authors: Khomeriki GG1, Darenkov SP1, Osmolovsky EO1, Okhobotov DA1
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Affiliations:
- Issue: No 3 (2004)
- Pages: 30-32
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/275260
- ID: 275260
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Abstract
Effects of low-molecular heparin flaxiparin on prevention of
thrombotic complications after radical prostatectomy were studied in
two groups of patients with localized formes of prostatic cancer at
stages Tic, T2a, T2b and T3a. Group 1 received non-fractionated
standard heparin in a dose 5000 units 4 times a day for 10 days. Group
2 was treated with flaxiparin in a dose 0.3 ml (7500 U anti-Xa) twice
a day s.c. for 10 days. After therapy no thromboembolic complications
were observed. In group 2 removal of the urethral catheter was conducted
4-5 days earlier than in group 1. This reduced hospital stay
from 29 to 20 days. Flaxiparin accelerated growing vessels in the zone
of urethrourethral or urethrovesical anastomosis resulting in improvement
of microcirculation and preventing strictures in the anastomotic
zone. Thus, low-molecular heparin prevents thromboembolic complications,
reduces hospital stay and duration of rehabilitation after
radical prostatectomy.
thrombotic complications after radical prostatectomy were studied in
two groups of patients with localized formes of prostatic cancer at
stages Tic, T2a, T2b and T3a. Group 1 received non-fractionated
standard heparin in a dose 5000 units 4 times a day for 10 days. Group
2 was treated with flaxiparin in a dose 0.3 ml (7500 U anti-Xa) twice
a day s.c. for 10 days. After therapy no thromboembolic complications
were observed. In group 2 removal of the urethral catheter was conducted
4-5 days earlier than in group 1. This reduced hospital stay
from 29 to 20 days. Flaxiparin accelerated growing vessels in the zone
of urethrourethral or urethrovesical anastomosis resulting in improvement
of microcirculation and preventing strictures in the anastomotic
zone. Thus, low-molecular heparin prevents thromboembolic complications,
reduces hospital stay and duration of rehabilitation after
radical prostatectomy.
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