Application of a free flap from urinarybladder mucosa for urethroplasty in experiment
- Authors: Kirpatovsky VI1, Kamalov AA1, Fedyakov RP1, Kudryavtsev Y.V1, Verzin AV1
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Affiliations:
- Issue: No 3 (2004)
- Pages: 35-40
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/275272
- ID: 275272
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Abstract
Experiments on 8 rabbits have demonstrated that mucosa of the
urinary bladder freely transplanted into the subcutaneous fat or under
the muscular fascia is engrafted with unaffected normal histological
structure and revascularized with vessels invading from the adjacent
tissues. Urethroplasty with a vesical mucosa graft was made in 10 dogs
with experimental urethral stricture (4 animals), urethral fistula (5 animals)
or a combination of urethral stricture and fistula (1 animal).
A positive result with reestablishment of normal urethral passability
and elimination of urinary fistula was achieved in 9 animals (follow-up
for 1 year). One dog died of an unknown cause. Urodynamic examination
of the dogs in long-term follow-up reported normal urethral
resistance to urinary flow.
urinary bladder freely transplanted into the subcutaneous fat or under
the muscular fascia is engrafted with unaffected normal histological
structure and revascularized with vessels invading from the adjacent
tissues. Urethroplasty with a vesical mucosa graft was made in 10 dogs
with experimental urethral stricture (4 animals), urethral fistula (5 animals)
or a combination of urethral stricture and fistula (1 animal).
A positive result with reestablishment of normal urethral passability
and elimination of urinary fistula was achieved in 9 animals (follow-up
for 1 year). One dog died of an unknown cause. Urodynamic examination
of the dogs in long-term follow-up reported normal urethral
resistance to urinary flow.
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