The role of a positive surgical margin after retropubic radical prostatectomy in prognosis of recurrent prostatic cancer

详细

To estimate the occurrence of positive surgical margins (SM) in conduction of radical retropubic prostatectomy and SM role in development of the recurrence, we studied 216 surgical patients with prostatic cancer aged 41 to 73 years. Stages T2a,b, ТЗа, Т1 and T3b were detected in 41.8, 35.6, 18.7 and 3.9% patients, respectively. A positive SM was verified in 68 of 193 (35.2%) patients. Of them, 36 (52.9%) patients had a focal (a single or short SM), while 32 (47.1%) patients had a long SM. The recurrence occurred in 31 (16.1%) cases, primarily in a long SM. In SM-free patients (group 1) one-year survival was 82% being very close to that in group 2 with a focal SM (83%). The differences between the groups were also minimal by three-year survival (75 and 73.6%, respectively). Thus, recurrence-free survival in the focal process and a short SM differs by three-year survival in the groups insignificantly. The period between month 12 and 24 is most risky in respect to recurrences in a short SM. Patients with a long SM had maximal number of prostatic cancer recurrences.