Cavernous vegetative innervation and hemodynamics in patients with fibroplastic induration of the penis and erectile dysfunction
- Authors: Dmitriev DG1, Permyakova OV1
-
Affiliations:
- Issue: No 5 (2005)
- Pages: 40-44
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/276639
- ID: 276639
Cite item
Full Text
Abstract
Different versions on pathogenesis of Peirony's disease (PD) and
erectile dysfunction in this disease made us to investigate cavernous
innervation and hemodynamics in patients with fibroplastic induration of the penis. We have detected characteristic changes of cavernous electric activity and histochemical picture in biopsies of all our patients with PD. Of them, 61% had cavernous hemodynamic disorders. Our findings suggest that early affection of cavernous innervation may trigger PD pathogenesis and erectile dysfunction in this disease.
erectile dysfunction in this disease made us to investigate cavernous
innervation and hemodynamics in patients with fibroplastic induration of the penis. We have detected characteristic changes of cavernous electric activity and histochemical picture in biopsies of all our patients with PD. Of them, 61% had cavernous hemodynamic disorders. Our findings suggest that early affection of cavernous innervation may trigger PD pathogenesis and erectile dysfunction in this disease.
References
- Лопаткин Н. А., Щеплев П. А., Мазаев А. П. Компьютерная томография в диагностике болезни Пейрони. Урол. и нефрол. 1982; 5: 29-33.
- Пытель А. Я., Мазо Е. Б. Фибропластическая индурация полового члена - болезнь Пейрони (Induratio penis plastika). Урол. и нефрол. 1963; 1: 64-73.
- Аляев Ю. Г., Рапопорт Л. М., Винаров А. 3. Комбинированная консервативная терапия болезни Пейрони. Врач, сословие. 2003; 2: 20-22.
- Дмитриев Д. Г., Пермякова О. В. Болезнь Пейрони. Materia Medica 2002; 1(33): 43-45.
- Сытенко А. М., Минченко П. П. Патофизиологические аспекты эректильной дисфункции у пациентов с болезнью Пейрони. Здоровье мужчины 2004; 1(8): 49-51.
- Bivalacqua Т. J., Champion H. С. Implications of nitric oxide synthase isoforms in the pathophysiology of Peyronie's disease. Int. J. Impotence Res. 2002; 14: 345-352.
- Wayne J. G. et al. Peyronie's disease: Etiology, medical, and surgical therapy. J. Androl. 2000; 21(3): 161 - 163.
- Levine L. A., Latchamsetty К. С. Treatment of erectile dysfunction in patients with Peyronie's disease using sildenafil citrate. Int. J. Impotence Res. 2002; 14: 478-482.
- Плаксин О. Ф. Эректильная дисфункция при болезни Пейрони (диагностика и лечение): Дис. ... канд. мед. наук. Челябинск, 2002.
- El-Sakka A. I. et al. Histological and ultrastructural alterations in an animal model of Peyronie's disease. J. Urol. (Baltimore) 1998; 158: 2284-2290.
- El-Sakka A., Hassan M., Nunes L. et al. Histological and ultrastructural alterations in an animal model of Peyronie's disease. Br. J. Urol. 1998; 81: 445-452.
- El-Sakka A. I., Selph С. A. et al. The Peyronie's disease is associated with the increase in transforming growth factor-бета protein expression. J. Urol. (Baltimore) 1998; 159: 1700-1707.
- Iacono F., Barra S. Microstructural disorders of tunica albuginea in patients affected by Peyronie's disease with or without erection disfunction. J. Urol. (Baltimore) 1993; 150: 1806-1809.
- Горпинченко И. И., Гурженко Ю. Н. Классификация болезни Пейрони. Андрол. и генит. хир. 2002; 3, прил.: 112.
Supplementary files
