INCIDENTAL RENAL CELL CARCINOMA: CLINICAL AND MORPHOLOGICAL FEATURES
- Authors: Bazayev V.V1, Dutov V.V1, Tyan P.A1, Kazantseva I.A.1
-
Affiliations:
- Issue: No 2 (2013)
- Pages: 66-69
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/279736
- ID: 279736
Cite item
Open Access
Access granted
Abstract
This article is devoted to the evaluation of features of incidental, or asymptomatic renal cell carcinoma (RCC). The study included 268 patients with RCC aged 25 to 92 years who underwent examination and treatment in the urological clinic MRSRCI for the last 5 years. 163 (60.8%) patients had incidental renal tumors (Group 1), 105 (39.2%) - symptomatic renal tumors (Group 2). In incidental renal tumors, tumor nodule was smaller compared with symptomatic RCC - 5,74 ± 3,0 vs 6,4 ± 3,6 cm. Stage I and II disease was diagnosed in 130 (79.7%) patients in Group 1 and only in 69 (65.7%) patients in Group 2 (P<0.05). No significant differences in the distribution of the degree of nuclear atypia according Fuhrman nuclear grade were identified. The organ preservation surgery were performed more frequently in incidental RCC than in symptomatic RCC, in 47 (28.9%) and 21 (20%) cases, respectively; in addition, regional and distant metastases were diagnosed less frequently. With this in mind, it should be suggested that incidental tumors have a better prognosis than tumors with clinical manifestations.
Keywords
Full Text
References
- Зубарев А.В., Гажонова В.Е., Зайцева Е.В. Диагностические возможности магнитно-резонансной, ультразвуковой и рентгеновской ангиографии при исследовании сосудов почек. Мед. визуализация. 2003;1:106-119.
- Kytikov A. et al. Incidence of beging pathologic findings at partial nefrectomy for solitary renal mass presumed to be renal cell carcinoma on preoperated imaiging. Urology. 2006;68(4):737-740.
- Jayson M., Sanders H. Increased incidence of serendipitously discovered renal cell carcinoma. Urology. 1998;51:203-205.
- Bretheau D. et al. Prognostic value of nuclear grade of renal cell carcinoma. Cancer. 1995;76(12):2543-2549.
- Rodriguez-Rubio F. et al. Incidentally detected renal cell carcinoma. Br. J. Urol. 1996;78:29-32.
- Dal Voglio M.F., Srougi M., Pierre D. et al. Morphologic of incidentally inentified renal tumors. Brazilian J. Urol. 2002;28(2):102—108.
- Гусев А.А. Клинико-морфологические особенности инцидентального почечно-клеточного рака. Автореф. дис. канд. мед. наук. М. 2007. 22 с.
- Mevorach R.A., Segal A J., Terswgno M.E. et al. Renal cell carcinoma: incidental diagnosis and natural history: review of235 cases. Urology. 1992;39(6):519-522.
- Patard J.J. et al. Prognostic significance of the mode of detection in renal tumours. BJU International. 2002;90(4):358-363.
- Luciana L.G., Cestari R., Tallarigo C. Incidental renal cell carcinoma - age and stage characterization and clinical implications: study of 1092 patients (1982-1997). Urology. 2000;56:58-62.
Supplementary files
