Mitomycin in the complex treatment of strictures of vesicourethral anastomosis after radical prostatectomy
- Authors: Artemov A.V1, Alyaev Y.G1, Rapoport L.M1, Tsarichenko D.G1
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Affiliations:
- First MSMU n.a. I.M. Sechenov Author for contacts: A.V. Artemov
- Issue: No 5 (2014)
- Pages: 77-81
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/280300
- ID: 280300
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Abstract
The study involved 189 patients aged 40 to 80 years, which underwent retropubic radical prostatectomy for localized prostate cancer in the period from 2009 to 2013. 26 (13.8%) patients required repeated surgery due to the deterioration of urination. In primary detection or recurrent nature of the cicatrical process in vesico-urethral anastomosis, in places of dissection by urethrotomic knife (or transurethral resection), surgery was complemented by submucosal injection of mitomycin, previously diluted in saline to a concentration of not more than 0.2 mg/ ml. Effectiveness of additional interstitial administration of mitomycin in primary application was 85%. Systemic infusion reactions have not been reported, that allows to consider this method as safe method for prevention of cicatricial complications.
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About the authors
A. V Artemov
First MSMU n.a. I.M. Sechenov Author for contacts: A.V. Artemov
Email: artie@mail.ru
SRI of Uronephrology and Human Reproductive Health
Yu. G Alyaev
First MSMU n.a. I.M. Sechenov Author for contacts: A.V. ArtemovSRI of Uronephrology and Human Reproductive Health
L. M Rapoport
First MSMU n.a. I.M. Sechenov Author for contacts: A.V. ArtemovSRI of Uronephrology and Human Reproductive Health
D. G Tsarichenko
First MSMU n.a. I.M. Sechenov Author for contacts: A.V. ArtemovSRI of Uronephrology and Human Reproductive Health
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