LONG-TERM OUTCOMES OF THE USE OF A-BLOCKERS TAMSULOSIN IN MEN WITH LOWER URINARY TRACT SYMPTOMS AND BENIGN PROSTATIC HYPERPLASIA
- Authors: Krivoborodov G.G1, Tur E.I1
-
Affiliations:
- RNSMU n.a. N.I. Pirogov of RMPH
- Issue: No 6 (2014)
- Pages: 47-50
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/280340
- ID: 280340
Cite item
Open Access
Access granted
Abstract
The retrospective evaluation of efficacy and safety of tamsulosin omnik (0.4 mg once a day) for 8 years in 17 patients with BPH and LUTS was performed. At the time of appointment of tamsulosin, mean age of patients was 61.9 years (range, 51 to 69 years). Efficacy of tamsulosin was evaluated based on the change of obstructive and irritative symptoms according to items of I-PSS scale, maximum urinary flow rate, residual urine volume and prostate volume. The study found that factors for favorable prognosis against the background of use of tamsulosin include moderate LUTS, small- or medium-sized BPH, maximum urinary flow rate of not less than 9 ml/s, and residual urine volume not more than 100 ml.
Full Text
About the authors
G. G Krivoborodov
RNSMU n.a. N.I. Pirogov of RMPH
Email: dr.krivoborodov@hotbox.ru
Department of Urology of the Medical Faculty prof. at the department
E. I Tur
RNSMU n.a. N.I. Pirogov of RMPHDepartment of Urology of the Medical Faculty
References
- Berry S.J., Coffey D.S., Walsh P.C. et al. The development o fhuman benign prostatic hyperplasia with age. J Urology. 1984;132(3): 474-479.
- Michel M.C., Vrydag W. a1-, a2- and b-adrenoreceptors in the urinary bladder, urethra and prostate. Br J Pharmacol 2006;147(Suppl. 2):S88-S119.
- Schulman C.C., Lock T.M., Buzelin J.M. et al. Long-term use of tamsulosin to treat lower urinary tract symptoms/benign prostatic hyperplasia. J Urol. 2001;166(4):1358-1363.
- Yamanishi T., Tatssumiya K., Furuya N. et al. Long-term efficacy of tamsulosin in the treatment of lower urinary tract symptoms suggestive of benign prostatic hyperplasia in real-life practice. UroToday International Journal. 2009;2(1).
- Kortmann B.B.M., Floratos D.L., Kiemney L.A. et al. Urodynamic effects of alpha-adrenoreceptor blockers: a review of clinical trials. Urology 2003;62(1): 1-9.
- Barendrecht M.M., Abrams P., Schumacher H. et al. Do a1-adrenoreceptor antagonists improve lower urinary tract symptoms by reducing bladder outlet resistance? Neurourol Urodyn 2008; 27 (3): 226-230.
Supplementary files
