Theeffectiveness of intracavernous autologous platelet-rich plasma in the treatment of erectile dysfunction


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Abstract

This article deals with using autologous platelet-rich plasma (APRP) as a new treatment for erectile dysfunction in men. In recent years there was a significant interest in regenerative medicine technology due to its high effectiveness with a good safety and low cost. Currently APRP has been used successfully in various fields of medicine (surgery, traumatology and orthopedics, sports medicine, cosmetics). However, until now there have been no studies consistent with evidence-based medicine verifying the effectiveness and long-term results of APRP application for ED treatment. This article presents the results of a clinical study on the use of APRP in men with ED with a comparative effectiveness analysis of different ways of APRP administration and in combination with PDE5 inhibitors. Possible mechanisms of action of APRP in restoring erectile function are discussed.

About the authors

M E Chalyj

Sechenov First Moscow State Medical University

Sechenov First Moscow State Medical University

V A Grigorjan

Sechenov First Moscow State Medical University

Sechenov First Moscow State Medical University

M V Epifanova

Research Institute of Uronephrology and Human Reproductive Health

Research Institute of Uronephrology and Human Reproductive Health

A O Krasnov

Sechenov First Moscow State Medical University

Sechenov First Moscow State Medical University

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