Factors affecting spermatogenesis preservation in rats with seminiferous tract obstruction


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Abstract

The aim of the study was to examine the effect of the seminal tract obstruction of different degree and duration on the morphological and functional condition of testicular tissue.
The study was conducted in 50 male Wistar rats. Three experimental models of seminiferous tract obstruction were set up: obstruction of the proximal part of the ductus deferens, obstruction of the distal part of the ductus deferens and obstruction of at the epididymis level. Morphological evaluation of testicular tissue was performed at 3 and 6 months after the obstruction. It was found that obstruction at the epididymis level caused the most severe impairment of spermatogenesis.

About the authors

S I Gamidov

'Department of Urology of RNRMU n.a. N.I. Pirogov

'Department of Urology of RNRMU n.a. N.I. Pirogov

R I Ovchinnikov

V.I. Kulakov Research Center of Obstetrics

V.I. Kulakov Research Center of Obstetrics

A Ju Popova

V.I. Kulakov Research Center of Obstetrics

V.I. Kulakov Research Center of Obstetrics

O M Krasova

'Department of Urology of RNRMU n.a. N.I. Pirogov

'Department of Urology of RNRMU n.a. N.I. Pirogov

M D Polivoda

Department of Experimental Surgery of Research Institute for Fundamental and Applied Biomedical Studies of RNRMUn.a. N.I. Pirogov

Department of Experimental Surgery of Research Institute for Fundamental and Applied Biomedical Studies of RNRMUn.a. N.I. Pirogov

E A Dubova

2nd Pathology and Autopsy Department of V.I. Kulakov Research Center of Obstetrics

2nd Pathology and Autopsy Department of V.I. Kulakov Research Center of Obstetrics

K A Pavlov

2nd Pathology and Autopsy Department of V.I. Kulakov Research Center of Obstetrics

2nd Pathology and Autopsy Department of V.I. Kulakov Research Center of Obstetrics

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