Experience with E. coli lyophilized bacterial lysate OM-89 (Uro-Vaksom®) in men with asymptomatic bacteriospermia
- Authors: Pochernikov DG1, Jakovleva LV1, Strelnikov AI1, Vinokurov EJ.1, Boldin DI1
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Affiliations:
- Ivanovo State Medical Academy
- Issue: No 4 (2015)
- Pages: 84-89
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/281837
- ID: 281837
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Abstract
Chronic prostatitis is a significant problem of modern urology because it is the most common urological disease among the male population. We consider a 3 month course of OM-89 (Uro-Vaksom®) the most rational treatment of asymptomatic bacteriospermia caused by not only
E. coli, but also by coexisting bacteria. Administration of OM-89 (Uro- Vaksom®) for 3 months to patients with asymptomatic bacteriospermia resulted in greater E. coli eradication in 98% of men and no growth of microorganisms in the ejaculate in 66%. Compared to these results, after a 3-4 week course of fluoroquinolones, E. coli occurred in significant titer in 15.2%, in non-significant - in 5.7% and the absence of microbial growth was noted only in 19% of cases. The course of OM-89 (Uro- Vaksom®), compared with fluoroquinolones, resulted in significantly increased sperm concentration and occurrence of greater number of spontaneous pregnancies. Rate of THB (Take Home Baby) for OM-89 (Uro-Vaksom®) group was 21%, for fluoroquinolones treatment group - 7%.
E. coli, but also by coexisting bacteria. Administration of OM-89 (Uro- Vaksom®) for 3 months to patients with asymptomatic bacteriospermia resulted in greater E. coli eradication in 98% of men and no growth of microorganisms in the ejaculate in 66%. Compared to these results, after a 3-4 week course of fluoroquinolones, E. coli occurred in significant titer in 15.2%, in non-significant - in 5.7% and the absence of microbial growth was noted only in 19% of cases. The course of OM-89 (Uro- Vaksom®), compared with fluoroquinolones, resulted in significantly increased sperm concentration and occurrence of greater number of spontaneous pregnancies. Rate of THB (Take Home Baby) for OM-89 (Uro-Vaksom®) group was 21%, for fluoroquinolones treatment group - 7%.
About the authors
D G Pochernikov
Ivanovo State Medical AcademyIvanovo State Medical Academy
L V Jakovleva
Ivanovo State Medical AcademyIvanovo State Medical Academy
A I Strelnikov
Ivanovo State Medical AcademyIvanovo State Medical Academy
E Ju Vinokurov
Ivanovo State Medical AcademyIvanovo State Medical Academy
D I Boldin
Ivanovo State Medical AcademyIvanovo State Medical Academy
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