RENAL TUMOR AND UROLITHIASIS: IS THERE A RELATIONSHIP?


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Abstract

There is conflicting evidence on the impact of urolithiasis on the risk of developing cancer of kidney and upper urinary tract. Most researchers are of the opinion that there is a definite association between the diseases and clinicians should take the necessary measures to detect possible malignancy of the kidney and upper urinary tract in patients with urolithiasis at the earliest stages. However, the pathophysiological mechanisms that may underlie the development of renal cell carcinoma and urothelial cancer in patients with urolithiasis remain unexplored.

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About the authors

Yu. G Alyaev

Sechenov First Moscow State Medical University

Moscow

A. M Pshikhachev

Sechenov First Moscow State Medical University, Research Institute of Uronephrology and Human Reproductive Health

Email: pshich@yandex.ru
PhD, Urologist at the Department of Urologic Oncology Moscow

E. V Shpot’

Sechenov First Moscow State Medical University

Email: shpot@inbox.ru
Moscow

G. N Akopyan

Sechenov First Moscow State Medical University

Email: docgagik@mail.ru
Moscow

A. V Proskura

Sechenov First Moscow State Medical University

Email: proskura777@yandex.ru
Moscow

References

  1. Trinchieri A. Epidemiology of urolithiasis. Arch. Ital. Uro. Androl. 1996;68(4):203-249.
  2. Sisodia S.M., Khan W.A., Bhavsar S.P. Incidental primary papillary mucinous adenocarcinoma of the renal pelvis in a case of nonfunctioning kidney due to chronic pyelonephritis and pelvic calculus. Saudi J. Kidney Dis. Transpl. 2012;23(3):592-593.
  3. Paonessa J., Beck H., Cook S. Squamous cell carcinoma of the renal pelvis associated with kidney stones: a case report. Med Oncol. 2011;28(1):392-394.
  4. Zarzour A.H., Selim M., Abd-Elsayed A.A., Hameed D.A., Abdelaziz M.A. Muscle invasive bladder cancer in Upper Egypt: the shift in risk factors and tumor characteristics. BMC Cancer. 2008;8:250.
  5. Chow W.H., Lindblad P., Gridley G., Nyren O., McLaughlin J.K., Linet M.S., Pennello G.A., Adami H.O., Fraumeni J.F. Risk of urinary tract cancers following kidney or ureter stones. J. Natl. Cancer. Inst. 1997;89(19):1453-1457.
  6. Sun L.M., Lin C.L., Chang Y.J., Liang J.A., Liu S.H., Sung F.C., Kao C.H. Urinary tract stone raises subsequent risk for urinary tract cancer: a population-based cohort study. BJU Int. 2013;112(8):1150-1155.
  7. Fekak H., Rabii R., Moufid K., Joual A., Dahami Z., el Mrini M. Unusual clinical presentations of tumours of the renal pelvis. Report of two cases. Prog Urol. 2002;12(3):482-485.
  8. Jain A., Mittal D., Jindal A., Solanki R., Khatri S., Parikh A., Yadav K. Incidentally detected squamous cell carcinoma of renal pelvis in patients with staghorn calculi: case series with review of the literature. ISRN Oncol. 2011;620574.
  9. Yeh C.C., Lin T.H., Wu H.C., Chang C.H., Chen C.C., Chen W.C. A high association of upper urinary tract transitional cell carcinoma with nonfunctioning kidney caused by stone disease in Taiwan. Urol. Int. 2007;79(1):19-23.
  10. Katz R., Gofrit O.N., Golijanin D., Landau E.H., Shapiro A., Pode D., Meretyk S. Urothelial cancer of the renal pelvis in percutaneous nephrolithotomy patients. Urol. Int. 2005;75(1):17-20.
  11. Аляев Ю.Г., Григорян З.Г., Крапивин А.А. Опухоль почки в сочетании с мочекаменной болезнью. Монография. М: Клиника урологии ММА им. И.М. Сеченова. 2005:224 с
  12. Leong C.H., Lim T.K., Wong K.K., Ong G.B. Carcinoma of the renal pelvis: an analysis of the diagnostic problems in 23 cases. Br. J. Surg. 1976;63(2):102-106.
  13. Okumura M., Hasegawa R., Shirai T.,Ito M., Yamada S., Fukushima S. Relationship between calculus formation and carcinogenesis in the urinary bladder of rats administered the non-genotoxic agents thymine or melamine. Carcinogenesis. 1992;13(6):1043-1045.
  14. Ogasawara H., Imaida K., Ishiwata H., Toyoda K., Kawanishi T., Uneyama C., Hayashi S., Takahashi M., Hayashi Y. Urinary bladder carcinogenesis induced by melamine in F344 male rats: correlation between carcinogenicity and urolith formation. Carcinogenesis. 1995;16(11):2773-2777.
  15. Chung S.D., Liu S.P., Lin H.C. A population-based study on the association between urinary calculi and kidney cancer. Can. Urol. Assoc. J. 2013;7(11 -12):716-721.
  16. Yoshikawa T.T., Nicolle L.E., Norman D.C. Management of complicated urinary tract infection in older patients. J. Am. Geriatr. Soc. 1996;44(10):1235-1241.

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