Teratozoospermia and karyopathological abnormalities in epithelial urogenital tract cells in male shift workers with varicocele in oil fields of the north of Siberia

  • Authors: Ilyinskikh N.N1,2, Ilyinskikh E.N2, Saushkin S.A2
  • Affiliations:
    1. Federal State Autonomous Educational Institution of Higher Education “National Research Tomsk State University” of the Ministry of Education and Science of the Russian Federation
    2. State Budgetary Educational Institution of Higher Professional Education “Siberian State Medical University” of the Ministry of Healthcare of the Russian Federation
  • Issue: No 4 (2016)
  • Pages: 82-86
  • Section: Articles
  • URL: https://journals.eco-vector.com/1728-2985/article/view/286474
  • ID: 286474

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Abstract

The purpose of the research: The aim of this work was to study associations between varicocele and the various types of karyopathologic abnormalities in epithelial urogenital tract cells or teratozoospermia in oil field shift workers of the north of Siberia. Materials and methods. We examined 139 male individuals in several oil field of the north of Tomsk and Tyumen regions. The examined individuals were divided in 4 groups: 1) driller-workers with varicocele; 2) driller-workers without varicocele; 3) oil field administrative staff with varicocele, and 4) oil field administrative staffwithout varicocele. Samples of both the sperm ejaculate and the epithelial urogenital tract cells were obtained from all the individuals for microscopic assay. Results. It was found that the frequencies of both the teratozoospermia and the various karyopathologic abnormalities in epithelial urogenital cells were significantly higher in the workers with varicocele compared to all the other groups. There were correlations between karyopathologic abnormalities in epithelial urogenital cells and teratozoospermia in both the driller-workers with varicocele and the oil field administrative staff with varicocele. However, the frequencies of damaged cells in this workers group were significantly higher than the ones in the administrative staff with varicocele, which can be associated with the genotoxic effects of work conditions at oil fields of the north of Siberia. Conclusions. From the data it was concluded that the increased frequencies of the abnormalities in the epithelial urogenital cells and the sperm in the driller-workers with varicocele may be associated with both the disease’s endogenous factor and the genotoxic effects of work conditions at the oil fields.

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About the authors

N. N Ilyinskikh

Federal State Autonomous Educational Institution of Higher Education “National Research Tomsk State University” of the Ministry of Education and Science of the Russian Federation; State Budgetary Educational Institution of Higher Professional Education “Siberian State Medical University” of the Ministry of Healthcare of the Russian Federation

Email: nauka-tomsk@yandex.ru
Sc.D. in Biology, Professor, Department of biotechnology

E. N Ilyinskikh

State Budgetary Educational Institution of Higher Professional Education “Siberian State Medical University” of the Ministry of Healthcare of the Russian Federation

Email: ilyinskikh@yandex.ru

S. A Saushkin

State Budgetary Educational Institution of Higher Professional Education “Siberian State Medical University” of the Ministry of Healthcare of the Russian Federation

Email: saushkin@yandex.ru

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