The role of drug therapy in the management of varicocele


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Abstract

Varicocele-related infertility is traditionally considered an indication for surgery. At the same time in some specific clinical settings, especially with subclinical varicocele, conservative therapy using hormonal or antioxidant drugs is also possible. The potential role of drug therapy in this patient category remains controversial. The article discusses the options and treatment regimens for men with varicocele-related infertility. Given the difficulties in interpreting the results of studies and the heterogeneity of the data, it is not yet possible to recommend abandoning varicocelectomy in favor of drug therapy. The most promising option for drug therapy is adjuvant antioxidants after surgical treatment of varicocele.

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About the authors

S. I Gamidov

V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology

Email: s_gamidov@oparina4.ru
Dr.Med.Sci. , Prof. at the Department of Obstetrics, Gynecology, Perinatology and Reproductology, IPE; Head of the Department of Andrology and Urology

V. M Popkov

Saratov State Medical University n. a. V. I. Razumovsky of Minzdrav of Russia

Email: meduniv@sgmu.ru
Dr.Med.Sci., Prof., Head of the Department of Urology

T. V Shatylko

Saratov State Medical University n. a. V. I. Razumovsky of Minzdrav of Russia

Email: shatylko@sar-urology.ru
Teaching Assistant at the Department of Urology

A. Yu Popova

V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology

Ph.D., Senior Researcher at the Department of Andrology and Urology

A. Yu Korolev

Saratov State Medical University n. a. V. I. Razumovsky of Minzdrav of Russia

Email: shatylko@sar-urology.ru
Ph.D., Teaching Assistant at the Department of Urology

R. I Ovchinnikov

V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology

Email: r_ovchinnikov@oparina4.ru
Ph.D., Head of the Department of Andrology and Urology

N. G Gasanov

V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology

Email: natiqhasan@gmail.com
Urologist at the Department of Andrology and Urology

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