Use of cytomedins in case of prostatic involvement in chronic prostatitis according to UPOINT classification
- Authors: Ergakov D.V1,2, Martov A.G1,2, Turin D.E1,2
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Affiliations:
- A.I. Burnazyan SRC FMBC, FMBA of Russia
- GBUZ “City clinical hospital named after D.D. Pletnev of the Health Department c. Moscow”
- Issue: No 3 (2019)
- Pages: 31-35
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/303631
- DOI: https://doi.org/10.18565/urology.2019.3.31-35
- ID: 303631
Cite item
Abstract
Background: chronic prostatitis is a common disease that significantIy influence on the quality of life. Aim: Our aim was to assess the prevaIence of particuIar domains of UPOINT cIassification and determine the efficiency of prostate- selective cytomedins in complex therapy of chronic prostatitis with the predominance of organic component. Materials and methods: a total of 96 patients aged from 24 to 48 years were treated in City clinical hospital named after D.D. Pletnev in 2017-2018 yy. with a previously diagnosed chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). The mean duration of the disease was 18.0±6.2 months. The total NIH-CPSI score was 24±7.3 (pain score 9±4.9, urinary score 7±2,7, quality of life 8±2.3), Qmax was l6±4.2 ml/s, prostate volume - 34±12 cc. Leukocyturia in post-massage urine was found in 52 patients (54%). Positive urine culture after prostate massage or positive bacterial semen study were found in 22 patients (23%). Prostate-specific therapy consisted of 20 days of rectal suppositories Vitaprost-forte® followed by oral therapy by Vitaprost® tablet of the same duration. Results: Follow-up examination of 72 patients (75%) was performed after 3 months of therapy. The total NIH-CSPI score decreased to 15.6±5.1 (pain score 6.3±3.8, urinary score 4.6±2.2, quality oflife 4.7±2), Qmax was 16±3.8 ml/s and mean prostate volume was 24±6 cc. The normalization of laboratory parameters was achieved in all cases. Conclusion: using the UPOINT classification allows to optimize the treatment of patients with chronic prostatitis. Use of prostate-specific cytomedins (Vitaprost®) is highly effective in case of prostatic involvement according to the UPOINT classification.
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About the authors
D. V Ergakov
A.I. Burnazyan SRC FMBC, FMBA of Russia; GBUZ “City clinical hospital named after D.D. Pletnev of the Health Department c. Moscow”
Email: dergakov@maiI.ru
Ph.D., urologist at the urologic department №2; associate professor at the Department of Urology and Andrology
A. G Martov
A.I. Burnazyan SRC FMBC, FMBA of Russia; GBUZ “City clinical hospital named after D.D. Pletnev of the Health Department c. Moscow”
Email: martovalex@mail.ru
MD, professor, Head of the urologic department №2; Head of the Department of Urology and Andrology
D. E Turin
A.I. Burnazyan SRC FMBC, FMBA of Russia; GBUZ “City clinical hospital named after D.D. Pletnev of the Health Department c. Moscow”Ph.D. at the Department of Urology and Andrology; urologist
References
- Аляев Ю.Г., Глыбочко П.В., Пушкарь Д.Ю. Урология. Российские клинические рекомендации. М.: Медфорум, 2017. 544 с.
- Engeler D., Baranowski A.P., Bergmans B. et al. EAU guidelines on chronic pelvic pain. Guidelines of the European Association of Urology, 2019.
- Polackwich A.S., Shoskes D.A. Chronic prostatitis/chronic pelvic pain syndrome: a review of evaluation and therapy. Prostate Cancer and Prostatic Diseases. 2016;1-7.
- Shoskes D.A., Nickel J.C. Classification and treatment of men with chronic prostatitis/chronic pelvic pain syndrome using the UPOINT system. World J. Urol. 2013;31(4):755-760. doi: 10.1007/s00345-013-1075-6.
- Ергаков Д.В., Мартов А.Г. Использование Витапрост (таблетки и ректальные суппозитории) для реабилитации пациентов после инвазивных диагностических урологических вмешательств. Урология. 2015;6:20-25
- Ергаков Д.В., Мартов А.Г. Применение ректальных суппозиториев Витапрост плюс до и после трансуретральной резекции предстательной железы. Урология. 2013;2:83-87
- Божедомов В.А. Современные возможности лечения хронического простатита. Андрология и генитальная хирургия. 2016;17:10-22
- Doiron R.C., Tripp D.A., Tolls V. et al. The evolving clinical picture of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS): A look at 1310 patients over 16 years. Can Urol Assoc J. 2018;12(6):196-202.