Analysis of urinary stone composition by infrared spectroscopy in the population of the European part of Russia


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Introduction. Urolithiasis is one of the most common urological diseases, which affect at least 3% of the population. Aim. To study the epidemiology of urolithiasis in the European part of the Russian Federation and to determine the composition of urinary stones in order to understand the pathogenetic mechanisms of urinary stones formation. Materials and methods. Urinary stone were obtained from 2888 patients with urolithiasis and the composition of kidney stones was analyzed using the method of infrared spectroscopy. Results. The predominance of oxalate stones was seen in kidney stones with mixed composition (83%) and the prevalence of uric acid stones (54%) was revealed in “pure” kidney stones. Urinary stones with a predominance of oxalates had significantly less impurities (12,4%) than stones with a predominance of uric acid, phosphates and carbonates with average amount of impurities more than 24%. Conslusion. The analysis of stone composition with a consideration of pathogenic factor showed that disorders of calcium metabolism in the population of the European part of the Russian Federation prevailed (88%).

Full Text

Restricted Access

About the authors

V. I Smirnova

Pavlov First Saint-Petersburg State Medical University

Email: nika_pion@mail.ru
biologist at the Scientific and Methodological Center for Molecular Medicine of the Ministry of Health Care of the Russian Saint-Petersburg

D. G Lebedev

Alexander Hospital; North-Western State Medical University named after I.I. Mechnikov

Head of the Department of ESWL in the Alexander Hospital Saint-Petersburg

S. V Lapin

Pavlov First Saint-Petersburg State Medical University

Ph.D., Head of Laboratory for Diagnostics of Autoimmune Diseases, Scientific and Methodological Center for Molecular Medicine of the Ministry of Health Care of the Russian Federation, Pavlov First Saint-Petersburg State Medical University Saint-Petersburg

V. L Emanuel

Pavlov First Saint-Petersburg State Medical University

Ph.D., MD, Prof., Head of the Department of clinical laboratory diagnostics with the course of molecular medicine, Director of the Scientific and methodological center of molecular medicine of the Ministry of health of the Russian Federation, Pavlov First Saint Petersburg State Medical University Saint-Petersburg

E. V. Rosengaus

North-Western State Medical University named after I.I. Mechnikov; Russian Scientific Center for Radiology and Surgical Technologies named after A.M. Granov

Ph.D., MD, Professor of the Department of X-ray Diagnostics and Radiation Therapy, radiologist of the highest category, North-Western State Medical University named after I.I. Mechnikov, Saint-Petersburg, Leading Researcher at the Department of X-ray Computed Tomography, Russian Scientific Center for Radiology and Surgical Technologies named after A.M. Granov Saint-Petersburg

References

  1. Chetverikov A.V. Goloshchapov Ye.T. Al'-Shukri S.KH. Emanuel' V.L. The influence of microbial factors on the stability of the colloidal properties of urine in urolithiasis. Eksperimental'naya i klinicheskaya urologiya. 2019;2:80-83.Russian @@Четвериков А.В. Голощапов Е.Т. Аль-Шукри С.Х. Эмануэль В.Л. Влияние микробных факторов на стабильность коллоидных свойств мочи при уролитиазе. Экспериментальная и клиническая урология. 2019;2:80-83.
  2. Lebedev D.G., Rozengauz Ye.V., Lapin S.V., Burlaka O.O., Khvastovskiy V.M. Possibilities of dual-energy spiral computed tomography in the analysis of the chemical composition of urinary stones. Luchevaya diagnostika i terapiya. 2017;3(8):110-111.Russian @@Лебедев Д.Г., Розенгауз Е.В., Лапин С.В., Бурлака О.О., Хвастовский В.М. Возможности двухэнергетической спиральной компьютерной томографии в анализе химического состава конкремента при мочекаменной болезни. Лучевая диагностика и терапия. 2017;3(8):110-111.
  3. Kaprin A.D., Apolikhin O.I., Sivkov A.V., Moskaleva N.G., Solntseva T.V. Analysis of uronephrological morbidity and mortality in the Russian Federation for 2003-2013. Eksperimental'naya i klinicheskaya urologiya. 2015;2:4-13.Russian @@Каприн А.Д., Аполихин О.И., Сивков А.В., Москалева Н.Г., Солнцева Т.В. Анализ уронефрологической заболеваемости и смертности в Российской Федерации за 2003-2013 гг. Экспериментальная и клиническая урология. 2015;2:4-13.
  4. Shevyrin A.A., Strelnikov A.I. Densitometric density of urinary stones as a predictive factor demonstrating their efficiency of disintegration in treatment of urolithiasis. Urol. Vedom 2019;8:17-24. doi: 10.17816/uroved8417-24.
  5. Kryuchkov I.A., Chekhonatskaya M.L., Rossolovskiy A.N. Urolithiasis: etiology and diagnosis (literature review). Byulleten' meditsinskikh Internet-konferentsiy (ISSN 2224-6150). 2017;7(2):517-522.Russian @@Крючков И.А., Чехонацкая М.Л., Россоловский А.Н. Мочекаменная болезнь: этиология и диагностика (обзор литературы). Бюллетень медицинских Интернет-конференций (ISSN 2224-6150). 2017;7(2):517-522.
  6. Cook J., Lamb B.W., Lettin J.E., Graham S.J. The Epidemiology of Urolithiasis in an Ethnically Diverse Population Living in The Same Area. Urol. J. 2016;13(4):2754-2758, doi: 10.22037/uj.v13i4.3336.
  7. Apolikhin O.I., Sivkov A.V., Komarova V.A., Prosyannikov M.YU., Golovanov S.A., Kazachenko A.V., Nikushina A.A. The incidence of urolithiasis in the Russian Federation (2005-2016). Eksperimental'naya i klinicheskaya urologiya. 2018;4:4-14.Russian @@Аполихин О.И., Сивков А.В., Комарова В.А., Просянников М.Ю., Голованов С.А., Казаченко А.В., Никушина А.А. Заболеваемость мочекаменной болезнью в РФ (2005-2016 годы). Экспериментальная и клиническая урология. 2018;4:4-14.
  8. Vitale C., Marangella M. Epidemiology of Nephrolithiasis. J Nephrol. 2000;13(3):S45-50. doi: 10.1002/9781118453926.ch103.
  9. Kalinina S.N. et al. Experience of treating patients with urolithiasis in the urological clinic of the Aleksandrovskaya hospital. Urol. Vedom. 2019;9(3):21-28. doi: 10.17816/uroved9321-28.
  10. TUrk C, Knoll T, Petrik A., Sarica K, Skolarikos A., Straub M, Seitz C., Dabestani S, Drake T., Grivas N., Ruhayel Y. Guidelines on urolithiasis. 2016.
  11. Han H., A.M. Segal, J.L. Seifter,J.T. Dwyer Nutritional Management of Kidney Stones (Nephrolithiasis). Clin. Nutr. Res. 2015;4(3):137. doi: 10.7762/cnr.2015.4.3.137.
  12. Chukhlovin A.B., Emanuel' YU.V. Napalkova O.V., Landa S.B. The role of local infections in urinary stone formation. Nefrologiia. 2011;15(3):11-17, Russian @@Чухловин А.Б., Эмануэль Ю.В. Напалкова О.В., Ланда С.Б. Роль локальных инфекций в генезе мочекаменной болезни. Нефрология. 2011;15(3):11-17. Doi: 616.62-003.7-092:616.9.
  13. Smirnova V.I., Lapin S.V., Lebedev D.G., Emanuel V.L., Malyshkin K.A., Blinova T.V. Validation of the infrared spectroscopy method for analysis of the composition of urine concretes. Klinicheskaya Laboratornaya Diagnostika (Russian Clinical Laboratory Diagnostics). 2021;66(12):733- 738 @@Смирнова В.И., Лапин С.В., Лебедев Д.Г., Эмануэль В.Л., Малышкин К.А., Блинова Т.В. Валидация метода инфракрасной спектроскопии для анализа состава мочевых конкрементов. Клиническая лабораторная диагностика. 2021; 66(12): 733-738. Doi: https//dx.doi.org/10.51620/0869-2084-2021-66-12-733-738
  14. Recurrence prevention of urolithiasis. EAU clinical guidelines, 2017. s. 16-29, 2017.Russian @@Метафилактика мочекаменной болезни. Клинические рекомендации EAU, 2017. C. 16-29, 2017.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies