Markers of stem cells and their prognostic values for urothelial carcinomas of the urinary tract
- Authors: Osmanov Y.I1,2, Kogan E.A1, Rapoport L.M3, Teodorovich O.V4,2, Gaibov J.A2
-
Affiliations:
- I.M. Sechenov First Moscow State Medical University
- Scientific Clinical Center of Russian Railways
- GBOU I.M. Sechenov First Moscow State Medical University
- NUZ NKC OAO “RJD”, FGBOU DPO RMANPO
- Issue: No 2 (2019)
- Pages: 40-49
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/322067
- DOI: https://doi.org/10.18565/urology.2019.2.40-49
- ID: 322067
Cite item
Abstract
Full Text
About the authors
Yu. I Osmanov
I.M. Sechenov First Moscow State Medical University; Scientific Clinical Center of Russian Railways
Email: osmanovyouseef@yandex.ru
Ph.D., head of the Department of Pathology of Scientific Clinical Center of Russian Railways; assistant professor of Department of Pathology named after A.I. Strukov
E. A Kogan
I.M. Sechenov First Moscow State Medical University
Email: koganevg@gmail.com
MD, professor, Head of the Department of Pathology named after A.I. Strukov
L. M Rapoport
GBOU I.M. Sechenov First Moscow State Medical University
Email: leonidrapoport@yandex.ru
MD, professor, Deputy Director for Clinical Care
O. V Teodorovich
NUZ NKC OAO “RJD”, FGBOU DPO RMANPO; Scientific Clinical Center of Russian Railways
Email: teoclinic1@gmail.com
MD, professor, Chief of urologic center, Head of the Department of endoscopic urology
J. A Gaibov
Scientific Clinical Center of Russian Railways
Email: jam_morf@list.ru
pathologist at the Department of Pathology
References
- He S., Nakada D., Morrison S.J. Mechanisms of stem cell self-renewal. Annu Rev Cell Dev Biol. 2009;25:377-406. https://doi.org/10.1146/ annurev.cellbio.042308.113248.
- Ginestier C., HurM.H., Charafe-Jauffret E., Monville F., Dutcher J., BrownM, Jacquemier J., Viens P., Kleer C.G., Liu S., Schott A., Hayes D., Birnbaum D., Wicha M.S., Dontu G. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell. 2007;1(5):555-67. doi: 10.1016/j.stem.2007.08.014.
- Kelly P.N., Dakic A., Adams J.M., Nutt S.L., Strasser A. Tumor growth need not be driven by rar.e cancer stem cells. Science. 2007;317(5836):337doi: 10.1126/science.1142596.
- Korpal M., Ell B.J., Buff a F.M., Ibrahim T., Blanco M.A., Celia-Terrassa T., Mercatali L., Khan Z., Goodarzi H., Hua Y., Wei Y., Hu G., Garcia B.A. Ragoussis J., Amadori D., Harris A.L., Kang Y. Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nat Med. 2011;17(9):1101-1108. doi: 10.1038/nm.2401.
- Chan K.S., Espinosa I., Chao M., Wong D., Ailles L., Diehn M., Gill H., Presti J. Jr., Chang H.Y., van deRijn M., Shortliffe L., Weissman I.L. Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proc Natl Acad Sci U. S. A. 2009;106(33):14016-14021. https://doi.org/10.1073/ pnas.0906549106
- Kurzrock E.A., Lieu D.K., Degraffenried L.A., Chan C.W., Isseroff R.R. Label-retaining cells of the bladder: candidate urothelial stem cells. Am J. Physiol Renal Physiol. 2008;294(6):F1415-1421. Doi: 10.1152/ ajprenal.00533.2007.
- Prasad S.M., Decastro G.J., Steinberg G.D., Medscape. Urothelial carcinoma of the bladder: definition, treatment and future efforts. Nat Rev Urol. 2011 Oct 11; 8(11):631-642. doi: 10.1038/nrurol.2011.144.
- Chan K.S., Volkmer J.P., Weissman I. Cancer stem cells in bladder cancer: a revisited and evolving concept. Curr Opin Urol. 2010;20(5):393-397. doi: 10.1097/MGU.0b013e32833cc9df.
- Philip L.H., Kurtova A., and Chan K.S. Normal and neoplastic urothelial stem cells: getting to the root of the problem. Nature Reviews Urology 2012;9:583-594. doi: 10.1038/nrurol.2012.142.
- Yang Z., Li C., Fan Z., Liu H., Zhang X., Cai Z., Xu L., Luo J., Huang Y., He L., Liu C., Wu S. Single-cell Sequencing Reveals Variants in ARID1A, GPRC5A and MLL2 Driving Self-renewal of Human Bladder Cancer Stem Cells. Eur Urol. 2017;71(1):8-12. doi: 10.1016/j.eururo.2016.06.025.
- Li C., Yang Z., Du Y., Tang H., Chen J., Hu D., Fan Z. BCMab1, a monoclonal antibody agai.nst aberrantly glycosylated integrin a3/31, has potent antitumor activity of bladder cancer in vivo. Clin Cancer Res. 2014;20(15):4001-4013. doi: 10.1158/1078-0432.CCR-13-3397.
- Edris B., Weiskopf K., Volkmer A.K., Volkmer J.P., Willingham S.B., Contreras-Trujillo H., Liu J., Majeti R., West R.B., Fletcher J.A., Beck A.H., Weissman I.L., van de Rijn M. Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma. Proc Natl Acad Sci U. S. A. 20120;109(17):6656-61. doi: 10.1073/pnas.1121629109.
- Li C., Du Y., Yang Z., He L., Wang Y., Hao L., Ding M., Yan R., Wang J., Fan Z. GALNT1-Mediated Glycosylation and Activation of Sonic Hedgehog Signaling Maintains the Self-Renewal and Tumor-Initiating Capacity of Bladder Cancer Stem Cells. Cancer Res. 2016;76(5):1273- 1283. doi: 10.1158/0008-5472.CAN-15-2309.
- Billerey C., Chopin D., Aubriot-Lorton M.H., Ricol D., Gil Diez de Medina S., Van Rhijn B., Bralet M.P., Lefrere-Belda M.A., Lahaye J.B., Abbou C.C., Bonaventure J., Zafrani E.S., van der Kwast T., Thiery J.P., Radvanyi F. Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors. Am J. Pathol. 2001;158(6):1955-1989. doi: 10.1016/50002-9440(10)64665-2.
- Thoman R., Maraia M., Ma N., Hammam O., Wishahi M., El Leithy T., Hiraku Y., Oikawa S., Kawanishi S. Nuclear localization of COX-2 in relation to the expression of stemness markers in urinary bladder cancer. Mediators Inflamm. 2012;2012:165879. doi: 10.1155/2012/165879.
- Peek E.M., Li D.R., Zhang H., Kim H.P., Zhang B., Garraway I.P., Chin A.I. Stromal modulation of bladder cancer-initiating cells in a subcutaneous tumor model. Am J. Cancer Res. 2012;2(6):745-751.
- Retz M.M., Sidhu S.S., Blaveri E., Kerr S.C., Dolganov G.M. CXCR4 expression reflects tumor progression and regulates motility of bladder cancer cells. Int J. Cancer. 2005;114(2):18-29. doi: 10.1002/ijc.20729.
- Overdevest J.B., Knubel K.H., Duex J.E. CD24 expression is important in male urothelial tumorigenesis and metastasis in mice and is androgen regulated. Proc Natl Acad Sci U. S. A. 2012;109(51):E3588-E3596. doi: 10.1073/pnas.1113960109.
- AiX., Zhang X., Wu Z., Ma X. Expression of KAI1/CD82 and MRP-1/CD9 in transitional cell carcinoma of bladder. J. Huazhong Univ Sci Technolog Med Sci. 2007;27(1):79-82. doi: 10.1007/s11596-007-0123-0.
- Amal Asar, Samia Gabal, Noha Helmy. Immunohistochemical study of the expression of Oct-4 in bladder urothelial carcinoma. Kasr Al Ainy Medical Journal. 2017, 23:141-147. doi: 10.4103/kamj.kamj_29_17.
- Mohd Khairul Anuar MD Akhir. Immunohistochemical expression of NANOG in urothelial carcinoma of the bladder. Malaysian J. Pathol 2017;39(3):227-234.
- Cheng L., Lopez-Beltran A., Bostwick D.G. Bladder pathology. Hoboken, N.J.: Wiley-Blackwell; 2012;161-283.
- Cheng L., Montironi R., Davidson D.D.,. Lopez-Beltran A. Staging and reporting of urothelial carcinoma of the urinary bladder. Mod Pathol. 2009;22(Suppl. 2):S70-S95. https://doi.org/10.1038/modpathol.2009
- Inamura K. Bladder Cancer: New Insights into Its Molecular Pathology. Cancers (Basel). 2018;10(4). pii: E100. doi: 10.3390/cancers10040100.
- Rajcani J., Kajo K., Adamkov M., Moravekova E., Lauko L., Felcanova D., Bencat M. Immunohistochemical characterization of urothelial carcinoma. Bratisl Lek Listy. 2013;114(8):431-438.
- Yasuyoshi Miyata, Yuji Sagara, Shinichi Watanabe. CD105 is a more appropriate marker for evaluating angiogenesis in urothelial cancer of the upper urinary tract than CD31 or CD34. Virchows Arch. 2013;463(5):673- 679. doi: 10.1007/s00428-013-1463-8.