Mechanisms of kidney damage


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Abstract

The results of recent studies on the mechanisms of kidney damage are presented in the review of literature. The role of the immune system in the occurrence, development and outcome of damage to the epithelium of the renal tubules, as well as molecular, genetic and metabolic changes which determine the extent and consequences of renal trauma are described in details. The mechanisms of restoration of the renal parenchyma and the development of fibrosis following the cessation of injury are given.

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About the authors

A. I Tarasenko

FGAOU VO I.M. Sechenov First Moscow State Medical University; Department of Medical Education Department and Personnel Policy in Health of Russia

Email: tarasenkoAl@rosminzdrav.ru
Ph.D., deputy director

A. V Alekseev

FGBOU VO “Bashkir State Medical University” of the Ministry of Health of the Russia

Email: alekseevdlt@mail.ru
Ph.D., Associate Professor at the Department of Urology with a course of IDPO

S. Yu Maksimova

FGBOU VO “Bashkir State Medical University” of the Ministry of Health of the Russia

Email: maksimova-serafima@mail.ru
assistant at the Department of Urology with a course of IDPO

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