Experience in performing robot-assisted radical prostatectomy in patients after heart transplantation

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Abstract

Introduction. Prostate cancer (PCa) occupies a leading position in the structure of oncological morbidity and mortality and is an urgent problem of modern oncourology. In recipients after organ transplantation, due to the intake of immunosuppressants, the risk of aggressive forms of cancer increases, which necessitates active treatment. In the world, there is not enough data on the radical treatment of PCa in patients after heart transplantation (HT), especially on surgical treatment. We present the first experience in Russia and Eastern Europe of 3 robot-assisted radical prostatectomy for localized PCa in patients after HT.

Materials and methods. The procedures were performed from February 2021 to November 2021 at the FGBU NMRC named after V.A. Almazov. Preoperative preparation, as well as postoperative management of patients was carried out jointly by urologists and transplant cardiologists.

Results. The main demographic, perioperative indicators, as well as oncological and non-oncological outcomes are presented. All patients were discharged from the hospital in a satisfactory condition. During the follow-up period, there were no biochemical recurrences of PCa. Early urinary continence in all three patients was satisfactory.

Conclusion. Thus, robot-assisted radical prostatectomy in patients after HT is a technically feasible, effective, and safe treatment for PCa. The comparative studies with prolonged follow-up are needed.

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About the authors

M. S. Mosoyan

FGBU NMRC named after V.A. Almazov of the Ministry of Health of the Russian Federation

Author for correspondence.
Email: moso03@yandex.ru
SPIN-code: 5716-9089
Scopus Author ID: 57208982777

Ph.D., MD, Head of the Department of Urology with Department of Urology with a course of Robotic surgery with a clinic; professor at the Department of Urology with a course of Robotic surgery with a clinic, Chief of the Center of Robotic Surgery

Russian Federation, Saint Petersburg

D. A. Shelipanov

FGBU NMRC named after V.A. Almazov of the Ministry of Health of the Russian Federation

Email: shelipanov_da@almazovcentre.ru

Ph.D., Head of the Department of Urology

Russian Federation, Saint Petersburg

P. A. Fedotov

FGBU NMRC named after V.A. Almazov of the Ministry of Health of the Russian Federation

Email: drheart@mail.ru
ORCID iD: 0000-0002-7452-1971

Ph.D., Head of the Research Laboratory of High-Tech treatment methods of heart failure

Russian Federation, Saint Petersburg

D. A. Fedorov

FGBU NMRC named after V.A. Almazov of the Ministry of Health of the Russian Federation

Email: tvoiurolog@gmail.com
ORCID iD: 0000-0002-6371-4620

assistant at the Department of Urology with Department of Urology with a course of Robotic surgery with a clinic

Russian Federation, Saint Petersburg

M. A. Simonenko

FGBU NMRC named after V.A. Almazov of the Ministry of Health of the Russian Federation

Email: dr.maria.simonenko@gmail.com
ORCID iD: 0000-0003-3228-1188

researcher of the Research Laboratory of Cardiopulmonary Testing, transplant cardiologist of Clinical and Diagnostic Center

Russian Federation, Saint Petersburg

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