The actual concept of salvage therapy for local recurrence prostate cancer after radical prostatectomy

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Abstract

Despite highly effective radical methods of treatment of prostate cancer (PC), 30% of patients will have a biochemical recurrence. The evolution in the diagnosis of recurrent prostate cancer after prostatectomy (RP) contributes to the search and development of such methods of treatment of relapses that consider not only the effectiveness, but also the quality of life of patients. This review demonstrates the actual concept of treatment of recurrent PC after RP, starting with salvage androgen-deprivation therapy with or without EBRT, and ending with minimally invasive methods such as salvage high-dose brachytherapy.

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About the authors

A. Yu. Pavlov

Russian Scientific Research Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation (RSCRR)

Email: mirzakhanov.ramil@ya.ru
ORCID iD: 0000-0002-2905-7735

Dr. Sci. (Med.), Professor, Deputy Director on scientific and curative work

Russian Federation, Moscow

A. G. Dzidzaria

Russian Scientific Research Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation (RSCRR)

Email: mirzakhanov.ramil@ya.ru
ORCID iD: 0000-0001-5789-375X

Dr. Sci. (Med.), Head of the Oncourology Department

Russian Federation, Moscow

A. D. Tsibulskii

Russian Scientific Research Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation (RSCRR)

Email: vracheg@mail.ru
ORCID iD: 0000-0002-1647-6180

Dr. Sci. (Med.), Senior Researcher of the Oncourology Department

Russian Federation, Moscow

R. I. Mirzakhanov

Russian Scientific Research Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation (RSCRR)

Author for correspondence.
Email: ha1zex@ya.ru
ORCID iD: 0000-0001-9739-4744

Postgraduate of the Department of Oncourology

Russian Federation, Moscow

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